NCT04634630CompletedNot Applicable
The Influence of Cancer Stem-cells on Risk of Relapse in Patients Harboring Adenocarcinoma and Squamous Cell Carcinoma of the Lung: a Prospective Cohort Study
Beatrice Aramini1 site in 1 country35 target enrollmentStarted: October 17, 2017Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- Relapse Free Survival
Study Overview
Brief Summary
The present study is a prospective cohort study. The aim is to assess the relationship between the presence of cancer stem-cells (CSC) and the risk of relapse in patients with early and locally advanced adenocarcinoma and squamous cell carcinoma of the lung
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients with stage I, II or IIIA adenocarcinoma of squamous cell carcinoma of the lung
- •age between 18 and 85
- •R0 resection
- •availability of formalin-fixed, paraffin-embedded surgery specimen from the primary tumor
- •availability of fresh surgical specimen for cytofluorimetric analysis
Exclusion Criteria
- •incomplete resection
- •unknown tumor, node or metastasis status
- •synchronous tumors
- •previous lung cancer
Outcomes
Primary Outcomes
Relapse Free Survival
Time Frame: Minimum follow-up time: 1 year
Days from lung cancer resection to relapse
Secondary Outcomes
No secondary outcomes reported
Investigators
Beatrice Aramini
Assistant Professor in Thoracic Surgery
Azienda Ospedaliero-Universitaria di Modena
Study Sites (1)
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