JPRN-UMIN000050122
Not yet recruiting
未知
A single-center, prospective, randomized, exploratory study to investigate the influence of ARNI (angiotensin receptor neprilysin inhibitor) in patients with hemodialysis and heart failure: SPREAD trial - Exploratory study to investigate the influence of ARNI in patients with hemodialysis and heart failure
Masuko Memorial Hospital0 sites374 target enrollmentFebruary 1, 2023
ConditionsChronic heart failure
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Chronic heart failure
- Sponsor
- Masuko Memorial Hospital
- Enrollment
- 374
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\)Patients who had hypotension before or during the last 3\-cycle hemodialysis 2\)Hyperkalemia 3\)Patients with severe liver disease 4\)Patients with a history of hospitalization due to ischemic heart disease or stroke within 3 months. 5\)Patients under an unstable heart failure condition 6\)Patients with a life expectancy less than 1 year 7\)Patients with acute phase disease requiring hospitalization 8\)Patients with severe valvular disease 9\)Patients with severe respiratory disease 10\)Pregnant patients 11\)Patients who are suspected of drug allergy to sacubitril\-valsartan 12\)Patients unable to communicate 13\)Patients who are judged inappropriate for this study by investigators
Outcomes
Primary Outcomes
Not specified
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