Effect of mannitol and hypertonic saline on brain tumor
Not Applicable
- Conditions
- brain tumor.G96.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- Registration Number
- IRCT20161126031091N2
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Supratentorial brain tumor patients without history of craniotomy
New onset brain tumor
Age above 18 and under 80
Exclusion Criteria
Metastatic brain tumor
Renal failure ( Cr>1.5)
Nephrotic syndrome
Heart rate <60
Diabetes melitus
Severe cardiopulmonary disorders
Uncontrolled high blood pressure
Age under 18 and above 80
Glasco Coma Scale under 6
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method S100B (a biomarker). Timepoint: operation day(before infusion of osmotic fluid) and 72 hours after surgery. Method of measurement: S100B mesuring with ELISA kit(Biovender).
- Secondary Outcome Measures
Name Time Method rine output (ml) during the operation. Timepoint: at the end of the operation. Method of measurement: by measuring of urine output collected in urine bag.;Bleeding volume(ml) during operation. Timepoint: at the end of the operation. Method of measurement: by measuring of bottle and used gauzes during the surgery.;Operating time. Timepoint: at the end of the operation. Method of measurement: by measuring time based on hours and minutes of start and end of operation.