Evaluation of the effects of preoperative administration of oral gabapentin on postoperative pai
Not Applicable
- Conditions
- Gabapentin.Other and unspecified antiepileptics
- Registration Number
- IRCT138810122963N1
- Lead Sponsor
- Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
women with American Society of Anesthesia (ASA) physical status I or II who are candidate for elective abdominal hysterectomy, age 40-60 years old, BMI
Exclusion criteria: Anaphylaxis reaction to the anesthetic drugs, duration of the operation longer than 2 hours
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain. Timepoint: 1,6,12,24 hours postoperatively. Method of measurement: visual analog pain score.;The first request of the patient for analgesic. Timepoint: during 24 hours after operation. Method of measurement: in hours.;Opioid (morphine) consumption. Timepoint: during 24 hours after operation. Method of measurement: mg morphine.
- Secondary Outcome Measures
Name Time Method Side effects of gabapentin (dizziness, blured vision, tremor, ataxia, nistagmus, nausea, vomitting). Timepoint: 1, 6, 12 and 24 hours after operation. Method of measurement: asking the patient, physical examination.;Systolic and diastolic blood pressures. Timepoint: 1, 6, 12 and 24 hours after operation. Method of measurement: In mnHg by Sphyngomanometer.;Heart rates. Timepoint: 1, 6, 12 and 24 hours after operation. Method of measurement: beats per minute in P/E.