Study of use of drugs used to treat bacterial infections and measuring vancomycin drug levels
Not Applicable
- Conditions
- Health Condition 1: K929- Disease of digestive system, unspecifiedHealth Condition 2: N289- Disorder of kidney and ureter, unspecifiedHealth Condition 3: R99- Ill-defined and unknown cause of mortalityHealth Condition 4: A498- Other bacterial infections of unspecified siteHealth Condition 5: G988- Other disorders of nervous systemHealth Condition 6: J22- Unspecified acute lower respiratory infectionHealth Condition 7: I999- Unspecified disorder of circulatory system
- Registration Number
- CTRI/2024/04/065210
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All consecutive patients in the age group of more than 1 month to 12 years who are newly admitted to the PICU and are started on antibacterial agents.
2.For estimation of vancomycin levels, 12 patients on vancomycin will be enrolled from amongst the above study participants.
Exclusion Criteria
Patients for whom the parents / guardians are not willing to give informed consent for participation will be excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Utilization of antibacterial agents as per the World Health Organization (WHO) drug use indicators. <br/ ><br>2. Indications of using antibacterial agents (empirical OR definitive OR prophylactic). <br/ ><br>3. Indications for change of antibacterial agents and escalation OR de-escalation of antibacterial agents. <br/ ><br>Timepoint: Duration of the PICU stay till discharge or death
- Secondary Outcome Measures
Name Time Method 1. Estimate the drug levels of vancomycin. <br/ ><br>2. Off-label use of antibacterial agents <br/ ><br>Timepoint: Duration of the PICU stay till discharge or death