Platelet reactivity testing in association with perioperative microembolic signals during carotid endarterectomy.
Completed
- Conditions
- Carotid artery stenosis10003216
- Registration Number
- NL-OMON36721
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Patients undergoing carotid endarterectomy
Exclusion Criteria
Patients requiring a blood transfusion prior to surgery
Patients with an inappropriate temporal bone window for TCD
Patients on vitamin K antagonists
Patients with an artificial cardiac valve
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Platelet reactivity (assessed by different tests: P-selectin FACS, VerifyNow,<br /><br>PFA-100), Microembolic signals detected by transcranial doppler, and clinical<br /><br>outcome. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>