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Clinical Trials/NCT04064996
NCT04064996
Completed
Not Applicable

Effectiveness of Foot Exercise Training on Patients With Type 2 Diabetes and Peripheral Neuropathy

Istanbul University1 site in 1 country34 target enrollmentApril 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetes Mellitus, Type 2
Sponsor
Istanbul University
Enrollment
34
Locations
1
Primary Endpoint
Pain assessment with Algometry
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of this study will to investigate the effect of foot exercises in patients with type 2 diabetic and peripheral neuropathy. Subjects will be randomly allocated to either the control or intervention group. Data will be collected using investigator-developed forms: patient information form and the diabetic foot exercises log. Patients in the intervention group will be received standard treatment and performed foot exercises for three times a week 8 weeks; the control group will be received standard treatment but no exercises. The intervention and control groups will be examined and measured at the 4th and 8th weeks.

Detailed Description

Purpose of our study investigation of the effects foot exercises in patients with type 2 diabetic and peripheral neuropathy. Excepted results: Routine treatment + foot exercises pain, flexibility, edema, muscle strength, sensation, quality of life we believe that there will be good progress in peripheral neuropathy effects, Leeds assessment of neuropathic symptoms and signs(LANSS) results. In this context, it is planned that patients randomly divided into 2 groups. Group 1 control group. Group 2 intervention group. Patients in the intervention group will be received standard treatment and performed foot exercises for three times a week 8 weeks. The patients will be evaluated by clinical measurements and scales based on patient notification at the 4th and 8th weeks.

Registry
clinicaltrials.gov
Start Date
April 1, 2019
End Date
November 30, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Evrim KOÇARSLAN

physiotherapist

Istanbul University

Eligibility Criteria

Inclusion Criteria

  • Having type 2 diabetes mellitus for 5 years
  • HbA1c \> among of between 6.5-10
  • Having grade 0 or 1 phase of Wagner classification
  • Diabetic neuropathy score ≥ 3

Exclusion Criteria

  • Not to know turkish
  • Having hearing, visual and speaking problems
  • Having (except diabetic neuropathy) other neurologic problems
  • Having psychiatric and cognitive problems
  • Having orthopedic, rheumatologic, cardiac, and pulmonary problems which stopping exercise

Outcomes

Primary Outcomes

Pain assessment with Algometry

Time Frame: Change from Baseline Pain at 8 weeks

An instrument for determining sensitivity to pain produced by pressure.

Pain assessment With Visual Analog Scale

Time Frame: Change from Baseline Pain at 8 weeks

Participants are asked to mark the point where they feel their pain on a 10 centimeter (cm) horizontal line. 0-no pain, 10-unbearable pain. Night, activity and pain conditions are evaluated separately at rest.

Pain assessment with The Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale

Time Frame: Change from Baseline Pain at 8 weeks

The Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) Pain Scale evaluates sensory dysfunction and whether the pain is caused by neuropathic mechanisms or not. The LANSS comprises a 5-item questionnaire regarding pain symptoms and two items for clinical signs involving self-administered sensory tests for the presence of allodynia and decreased sensation to pinprick. Responses to each item are binary (yes or no) and each item is weighted differently depending on the odds ratio of a positive response to each item to predict that the pain is primarily neuropathic. The possible scores range from 0 to 24, with a score of 12 or greater considered to be suggestive of neuropathic pain

Secondary Outcomes

  • Muscle Strength with Hand held dynamometer(1th day, 8th week)
  • Range Of Motion with goniometer(1th day, 8th week)
  • Baseline Tactile Semmes-Weinstein Monofilament(1th day, 8th week)
  • Edema measurement of tape(1th day, 8th week)
  • Two Point Discrimation Test(1th day, 8th week)
  • The Foot and Ankle Ability Measure(1th day, 8th week)
  • HbA1c(1 th day, 8th week)
  • Serum creatinine(1 th day, 8th week)
  • Evaluation of functional capacity with 6 minutes walking test(1th day, 8th week)
  • Albumin levels(1 th day, 8th week)

Study Sites (1)

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