Reconstruction of the optic radiation using enhanced DTI compared to HARDI

Completed

• Conditions: Epilepsy; falling sickness; 10029305

• Registration Number: NL-OMON40269
• Lead Sponsor: Epilepsiecentrum Kempenhaeghe

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

* > 18 and < 65 years;
* no structural abnormalities based on earlier MR scans;
* no suspicion of further neurological disorders.
* written agreement that unexpected findings will be reported to the person (general practitioner or other medical specialist) as indicated by the volunteer on the MRI checklist;
* subjects should give a written informed consent. The informed consent gives each participant thorough understanding of the purpose, nature and procedures of the examinations and explains the voluntariness of the examinations and the confidentiality of the patients data.

Exclusion Criteria

* who cannot meet the mild physical or psychological criteria for prolonged MRI scanning;
* who have a cardiac pacemaker or intracranial metals.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>An estimate of the anatomically plausible OR tracts for the three datasets as<br /><br>described earlier, which is based on the percentage of fibers that remain after<br /><br>all implausible OR tracts are removed from those produced by the probabilistic<br /><br>tracking algorithm. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>As secondary study parameter the plausibility of the fiber distribution will be<br /><br>evaluated compared to the anatomy. </p><br>