The effect of of photodynamic therapy with methylene blue on the treatment of cutaneous leishmaniosis

Phase 2

Recruiting

• Conditions: Cutaneous leishmaniasis.; Cutaneous leishmaniasis; B55.1

• Registration Number: IRCT20200803048289N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

Newly diagnosed localized cutaneous leishmaniasis confirmed by smear Giemsa sample
Less than 12 weeks has elapsed since the onset of the lesion
No lesion on face
Number of lesions is less than four
No sporotricoid form
Size of lesion is less than 5 centimeters
The lesion is not on joints.
Urban leishmaniasis (based on patient's clinical observations and regional epidemiology)

Exclusion Criteria

Pregnancy and breastfeeding
Existence of serious or severe underlying diseases (such as heart disease, kidney disease, liver disease, immunodeficiency)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ilcer development and complete lesion epithelialization in ulcerative lesions. Timepoint: Before, during and 12 weeks after the end of treatment. Method of measurement: Clinical observations.;Becoming flat and change in induration diameter in non-ulcerative lesions. Timepoint: Before, during and 12 weeks after the end of treatment. Method of measurement: Clinical observations.;Diameter of induration and erythema and ulcer size. Timepoint: Before, during and 12 weeks after the end of treatment. Method of measurement: Ruler and caliper.