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Evaluation of the photodymanic effect of methylene blue dilluted in detergent for the ancillary treatment of periodontal disease

Not Applicable
Recruiting
Conditions
Periodontitis
C07.465.714.533
Registration Number
RBR-2g9cf4
Lead Sponsor
Associação Educacional Nove de Julho
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Have stage III periodontitis, grade B; have at least 10 teeth present with probing depth greater than or equal to 5 mm; clinical attachment level greater than or equal to 5 mm; bleeding index to probing less than 30%; minimum age of 18 years; both genders

Exclusion Criteria

Smokers; diabetics; patients with anemia; cancer; pregnant; antibiotic use in the last 6 months; anti-inflammatory use in the last 3 months

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the action of methylene blue in a solution of 0,25% sodium dodecylsulfate in phosphate-buffered saline as an adjunct to the treatment of periodontitis, verifying the amount of colony forming unit of microbiological samples collected before and after the application of antimicrobial photodynamic therapy
Secondary Outcome Measures
NameTimeMethod
To compare the effect of methylene blue in phosphate-buffered saline with methylene blue in a solution of 0,25% sodium dodecylsulfate in phosphate-buffered saline; evaluating the reduction of periodontal pockets through the following periodontal clinical parameters: clinical probing depth, which measures the distance between the gingival margin and the bottom of the pocket; the bleeding on probing index; and the clinical attachment level, which measures the distance between the enamel-cement junction and the bottom of the pocket
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