Ablation zone delineation with MRI during thermal ablation of liver tumours

Phase 2

Completed

• Conditions: Liver cancer; liver tumors; 10019815; 10019818

• Registration Number: NL-OMON45796
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- Age 18 years and over.
- Indication for liver RFA/MWA treatment assessed by the multidisciplinary liver tumor board.
- Written (signed and dated) informed consent.

Exclusion Criteria

- Insufficient command of the Dutch language to be able to understand the patient information.
- Pregnancy
- Contraindications for MRI
- Contraindications for liver RFA/MWA treatment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome is the feasibility of real-time MRI temperature monitoring and<br /><br>ablation zone assessment during thermal ablation of hepatic malignancies. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes are correlation of per-procedural MRI-guided delineated<br /><br>ablation zone with the ablation zone depicted on follow-up CT six weeks after<br /><br>treatment and the predicted ablation zone by manufacturer specifications, and<br /><br>the influence of patient and procedure characteristics on whether the predicted<br /><br>ablation zone is reached.</p><br>