The Peri-Operative Epidural Trial pilot study

Completed

• Conditions: Postoperative cardio-respiratory complications; Circulatory System

• Registration Number: ISRCTN35629817
• Lead Sponsor: Vancouver Coastal Health Research Institute, University of British Columbia (Canada)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Any patient undergoing non-cardiopulmonary surgery who:
1. Is greater than or equal to 45 years old, either sex
2. Has an expected length of stay greater than or equal to 48 hours
3. Is undergoing a procedure amenable to postoperative epidural analgesia
4. Fulfils any six criteria for moderate to high cardiorespiratory risk

Exclusion Criteria

1. Is pregnant or planning to become pregnant before surgery
2. Has a contraindication to epidural analgesia
3. Had a prior adverse reaction to local anesthetics or narcotics
4. Had coronary artery bypass graft surgery with complete revascularisation in the preceding 5 years and has no evidence of cardiac ischemia since the procedure
5. Has pneumonia in the preoperative period
6. Is intubated or mechanically ventilated prior to surgery
7. Has concomitant life-threatening disease likely to limit life expectancy to less than 30 days

Study & Design

• Study Type: Interventional
• Study Design: Not specified