Quantifying Iron Absorption, Loss and Balance in Endurance Trained Athletes Across a 12-Month Training Cycle

Not Applicable

Completed

• Conditions: Iron deficiency; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12621001580864
• Lead Sponsor: Australian Catholic Univeristy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-18
• Study Completion: 2024-06-01
• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 57

Inclusion Criteria

Three different cohorts will be recruited:

1. Highly trained male runners and race walkers with a minimum training volume of ~50 km/week.
2. Highly trained female runners and race walkers with a minimum training volume of ~50 km/week. Participants will have regular menstrual cycles (>9 per year; naturally menstruating or on hormonal contraception)
3. Male, recreationally active individuals, not performing more than 2 endurance based exercise sessions per week.

Exclusion Criteria

Free from lifestyle and/or metabolic diseases (i.e. obesity, diabetes)
BMI >30 kg/m2
Do not meet the required exercise volume
Experience large blood loss (surgery/blood donation/pregnancy).

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in iron isotope composition in the blood[ Blood samples will be collected on 5 occasions, each separated by a 3 month interval (12, 15, 18, 21 and 24 months post stable iron isotope tracer administration). ]

Secondary Outcome Measures

Name	Time	Method
Dietary Intake[ The Dietary Questionnaire for Epidemiological Studies Version 3.2 (DQES v3.2) will be administered on 5 occasions at 3 monthly intervals to capture changes to dietary intake across the 12 month observation period. The questionnaire will be completed at 12, 15, 18, 21 and 24 months post stable iron isotope tracer administration];Training Volume [ In athletes, weekly millage (kilometers travelled per week) will be collected over the 12 month period. In recreationally active participants, the International Physical Activity Questionnaire (Long, Last 7 days self-administered format) will be implemented on 5 occasions at 3 month intervals to determine habitual physical activity levels.<br><br>The questionnaire will be completed at 12, 15, 18, 21 and 24 months post stable iron isotope tracer administration]