Probiotics in the prevention of traveller's diarrhoea.
- Conditions
- Traveller's diarrhoea, TD, traveller's diarrhea, probiotics, double blind RCT, lactobacillus, bifidobacterium
- Registration Number
- NL-OMON23250
- Lead Sponsor
- AMC Tropencentrum.
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 800
1. Both male and female adults (+18);
2. Travelling to high risk area's for TD (Midle east, Asia, South and Central America, North Africa);
3. Duration of travelling: min. 7 days, max. 28 days;
4. People who experienced TD before;
5. All new travellers to high risk area's
1. Use of antibiotics until two weeks before leaving;
2. Use of laxatives, acid blockers and diarrhoea inhibitors;
3. Persons who already have complaints about their stomach and/or intestines;
4. IBS/IBD and stoma patients;
5. Pregnant or breastfeeding women;
6. Patients with a serious disturbed or fragile/weak immune system (according to LCR criteria);
7. Use of probiotics two weeks before start of journey;
8. Frequent traveller's to high risk area's who never had TD complaints.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Consistency of stools according to Bristol scale;<br>2. Frequency of stools.
- Secondary Outcome Measures
Name Time Method Duration of traveller's diarrhoea<br>