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PRoactive Management Of Depression in the Elderly.

Conditions
Depressive symptoms
Registration Number
NL-OMON28191
Lead Sponsor
eiden University Medical Center, department of Public Health and Primary Care.
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
4000
Inclusion Criteria

1. Inclusion criteria for screening: elderly aged 75 years and over enlisted in general practices;
2. Inclusion criteria for treatment-offer: screen positive for depression (GDS-15 > 4).

Exclusion Criteria

1. Exclusion criteria for screening: terminal illness, current treatment for depression, loss of partner/important relative within previous 3 months;
2. Exclusion criteria for treatment-offer: severe cognitive impairment (MMSE < 19).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Difference in severity of depressive symptoms (MADRS baseline - 6 months).
Secondary Outcome Measures
NameTimeMethod
Differences (at 6 and 12 months) in: <br>1. Percentage responders to treatment;<br>2. Quality of life (SF-36, EQ-5D);<br>3. Mortality;<br>4. Use of (in)formal help or home care;<br>5. Medical consumption;<br>6. Cost-effectiveness;<br>7. Costs per QALY.
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