The effect of a new peripheral nerve block, popliteal plexus block, on postoperative opioid use, postoperative pain, muscle strength of the leg and mobilization after total knee replacement surgery - a randomized, controlled, blinded study
- Conditions
- Postoperative pain following a total knee arthroplasty surgeryMedDRA version: 21.1Level: LLTClassification code 10036236Term: Postoperative pain reliefSystem Organ Class: 100000004865Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2021-000242-17-DK
- Lead Sponsor
- Region Hospital Silkeborg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 165
Scheduled to undergo primary total knee arthroplasty in spinal anesthesia
Able to perform a Timed Up and Go (TUG) test
Age > 50 years old
Ability to give their written informed consent to participating in the study after having fully understood the contents of the study
American Society of Anesthesiologists (ASA) physical status 1, 2, or 3
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 45
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 120
Patients who cannot cooperate
Patients who cannot understand or speak Danish.
Patients with allergy or intolerance to the medicines used in the study
Patients with a daily intake of strong opioids (morphine, oxycodone, ketobemidone, methadone, fentanyl)
Patients suffering from alcohol and/or drug abuse – based on the investigator's assessment
Diagnosed with chronic central or peripheral neurodegenerative disorders
Body Mass Index > 40
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method