Implication of Left veNtricle Vortex Flow Guided aNticOagulation Therapy for preVenting Apical Thrombus Formation In Patients With Acute myOcardial infarctioN: Multicenter Prospective Randomized Clinical Trial; INNOVATION Study
Completed
- Conditions
- Apical Thrombus FormationAcute Myocardial Infarction
- Registration Number
- NCT01869998
- Lead Sponsor
- Yonsei University
- Brief Summary
Implication of left veNtricle vortex flow guided aNticOagulation therapy for preVenting Apical Thrombus formation In patients with acute myOcardial infarctioN: Multicenter Prospective Randomized Clinical Trial; INNOVATION study
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 111
Inclusion Criteria
- Patient is ≥ 30 years old
- Acute anterior wall myocardial infarction showing akinetic or dyskinetic apical wall motion abnormalities on an initial transthoracic echocardiogram
- Left ventricular ejection fraction less than 40%
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Exclusion Criteria
- Prior history of myocardial infarction
- Chronic medication with Coumadin
- Contraindication of contrast echocardiography
- Significant atrial or ventricular arrhythmia
- Valvular heart disease more than moderate degree
- Decompensated heart failure
- Very poor echo window, which cannot evaluate the presence of apical thrombus
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Apical thrombus formation in echocardiography 30 days after initial echocardiography Evaluate and compare the incidence of thrombus formation in high risk group (Vortex depth \< 0.45) and low risk group (Vortex Depth ≥ 0.45)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Severance cardiovascular hospital
🇰🇷Seoul, Korea, Republic of