Intravenous Versus Intra-peritoneal Dexamethasone on the Incidence of Postoperative Nausea and Vomiting

Not Applicable

Completed

• Conditions: Postoperative Nausea and Vomiting
• Interventions: Drug: Intravenous Dexamethasone; Drug: Intraperitoneal Dexamesathone

• Registration Number: NCT02947672
• Lead Sponsor: Assiut University

Brief Summary

Effect of intravenous versus intra-peritoneal dexamethasone on the incidence of postoperative nausea and vomiting following Laparoscopic gynecological surgeries.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-10-24
• Study First Submitted QC: 2016-10-26
• Study First Posted: 2016-10-28
• Study Start: 2016-11
• Primary Completion: 2017-11
• Study Completion: 2017-11
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-11
• Last Update Posted: 2018-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. Adult Female patients
2. American society of anesthesiologist class I & II
3. Undergoing Laparoscopic gynecological surgeries

Exclusion Criteria

1. Patient refusal to participate in the study
2. Patients with coagulopathy or under anticoagulation therapy.
3. Infection near the site of needle insertion.
4. Body mass index > 40kg/m2
5. Patients with any neurological or neuromuscular disorder or history of seizures.
6. Known allergy to any drug used in the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intravenous dexamethasone	Intravenous Dexamethasone	50 patients will receive intravenous dexamethasone
Intra peritoneal dexamethasone	Intraperitoneal Dexamesathone	50 patients will receive intraperitoneal dexamethasone

Primary Outcome Measures

Name	Time	Method
Postoperative nausea and vomiting (PONV)	24 hours	PONV will be measured by using Verbal Descriptive Scale

Secondary Outcome Measures

Name	Time	Method
Pain	24 hours	Pain will be assessed by using visual analogue scale

Trial Locations

Locations (1)

Assiut University Hospital; 🇪🇬 Assiut, Egypt