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Clinical Trials/NCT06104436
NCT06104436
Not Yet Recruiting
N/A

The Effects of an Individualized Music Playlist Based on the ISOPrinciple for the Immediate De-escalation of Agitation in People With Dementia: a Randomized Controlled Trial

The Hong Kong Polytechnic University1 site in 1 country81 target enrollmentMarch 1, 2024
ConditionsDementia

Overview

Phase
N/A
Intervention
Not specified
Conditions
Dementia
Sponsor
The Hong Kong Polytechnic University
Enrollment
81
Locations
1
Primary Endpoint
Agitation status
Status
Not Yet Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to evaluate the efficacy of an Individualized Music Playlist (InMP) composed of preferred music genres sequenced according to the ISO-Principle, for the immediate de-escalation of agitation in dementia, compared with preferred music (PM) and treatment as usual (TAU).

Detailed Description

1. Study design - Randomized controlled trial 2. Participants - Eighty-one older adults living with dementia and demonstrate significant agitation 3. Setting: - Residential care home 4. Intervention - Individualized music listening intervention played with an iPad and a wireless neckband speaker for 30 minutes when agitation begins in addition to usual care. 5. Comparison conditions * Preferred music listening group: Preferred music listening played with an iPad and a wireless neckband speaker for 30 minutes when agitation begins in addition to usual care. * Usual care group: usual care 6. Outcomes * Level of agitation measured with the Pittsburgh Agitation Scale * Intensity of agitation measured with the Positive and Negative Syndrome Scale - Excited Component * Agitation occurrence frequency measured with Cohen-Mansfield Agitation Inventory * Distress of formal caregivers related to agitation measured with Neuropsychiatric Inventory 7. Focus group interviews with the care staff will be conducted as a process evaluation for identifying the potential facilitators and barriers related to implementation.

Registry
clinicaltrials.gov
Start Date
March 1, 2024
End Date
December 31, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • residents in long-term care facilities
  • diagnosed with any type of dementia
  • presented with significant agitation

Exclusion Criteria

  • had been admitted to the facility for less than three months
  • are participating in other studies or experimental therapies
  • have a comorbid psychiatric illness
  • have physical illness that prevents them from listening to music

Outcomes

Primary Outcomes

Agitation status

Time Frame: 6 weeks

Behavioural Activity Rating Scale will be used to assess the agitation status. It contains a single-item question consisting of seven categories: 1=difficult or unable to rouse; 2=asleep, but responds normally to verbal or physical contact; 3=drowsy, appears sedated; 4=quiet and awake (normal level of activity); 5=signs of overt (physical or verbal) activity, calms down with instruction; 6=extremely or continuously active, not requiring restraint; 7=violent, requires restraint.

Level of agitation

Time Frame: 6 weeks

Positive and Negative Syndrome Scale - Excitatory Component will be used for assessing the level of agitation. It consists of 5 items: excitement, tension, hostility, uncooperativeness, and poor impulse control. The 5 items from the PANSS-EC are rated from 1 (not present) to 7 (extremely severe); scores range from 5 to 35; mean scores ≥ 20 clinically correspond to severe agitation.

Intensity of agitation

Time Frame: 6 weeks

Pittsburgh Agitation Scale will be used to assess the intensity of agitation. It is a brief measure of agitation that measures the severity of agitation in four general categories: aberrant vocalisation, motor agitation, aggressiveness and resisting care, on a scale from 0 (not present) to 4 (highest level).

Secondary Outcomes

  • Agitation occurrence(6 weeks)
  • Emotional or psychological distress of carer(6 weeks)

Study Sites (1)

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