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Clinical Trials/NCT04110691
NCT04110691
Unknown
Not Applicable

Impact of Stent Length and Diameter on Short Term Outcomes in Patients With ST Segment Elevation Myocardial Infarction Undergoing Primary PCI.

Assiut University0 sites200 target enrollmentJuly 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
ST-segment Elevation Myocardial Infarction (STEMI)
Sponsor
Assiut University
Enrollment
200
Primary Endpoint
prognosis of patients with ST segment myocardial infarction undergoing primary PCI
Last Updated
5 years ago

Overview

Brief Summary

The goal of the study is to evaluate the Impact of coronary stent length and/or diameter in patients with ST segment myocardial infarction undergoing primary PCI, on Short term clinical outcomes.

Detailed Description

* ST segment elevation myocardial infarction is serious condition to the blood supply to the heart muscle. Rapid reperfusion of the ischemic myocardium using percutaneous coronary intervention (PCI) is the standard treatment for acute myocardial infarction (MI) to rescue the ischemic myocardium and reduce infarction size. * There are two types of stents: 1. Drug-eluting stent which achieving local drug delivery to the injured blood vessel at the time of intervention, a drug is released from a polymer coating or loaded directly onto the stent (2). This is the best one. 2. Bare metal stent is the old one and not effective as DES in reducing vascular restenosis by suppressing smooth muscle cell (SMC) proliferation. * The management of long coronary lesions by percutaneous coronary intervention (PCI) has become increasingly important because of the rising incidence of long or complex lesions in aging populations (3) Stent length has been considered as an important predictor of adverse events after PCI. The exact impact of lesion length on the short- and long-term clinical outcomes of DES implantations is not clear yet. * Myocardial necrosis complicates one-third of percutaneous coronary intervention (PCI) and may adversely affect the outcome(4)

Registry
clinicaltrials.gov
Start Date
July 1, 2020
End Date
January 28, 2022
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nada Deyaa

Principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Patients with ST segment myocardial infarction who are eligible for PCI.
  • All categories (all age groups and both sex groups)

Exclusion Criteria

  • Patients with previous PCI.
  • Patients of ectatic lesions.
  • Patients with with multi vessel disease and suitable for CABG.
  • Patients with complex lesions including bifurcational lesions and LM stenting.

Outcomes

Primary Outcomes

prognosis of patients with ST segment myocardial infarction undergoing primary PCI

Time Frame: 3 months

prognosis will be measured with ECG and ECHO

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