The effect of dexamethasone on reducing pain after cesarean section in pregnant women referred to Kosar Hospital in Qazvin 1399

Phase 3

Recruiting

Conditions: The effect of intravenous dexamethasone injection on pain after cesarean section.

Registration Number: IRCT20210110049996N1

Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 88

Inclusion Criteria

Gestational age> = 37 weeks
Age over 18 years and no history of specific disease
Uncomplicated pregnancy
Elective cesarean section (breech, meconium, macrosome, ripit 2)
Absence of previous laparotomy incision except cesarean section

Exclusion Criteria

contraindications to spinal anesthesia
allergy to study medications
uncontrolled hypertension
uncontrolled diabetes mellitus
glaucoma
IV drug abuse
, chronic pain or long-term opioid use
steroid medication within the week prior to cesarean delivery
subjects with psychiatric illness that would prohibit informed consent or comprehension of the study questions
repeat 3 cesarean section or more than two laparotomies
chorioamnionitis
Intra-abdominal adhesions

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect of intravenous dexamethasone on pain after cesarean section. Timepoint: 6,12,18,24 hour after surgery. Method of measurement: Both baseline preoperative and postoperative pain scores at rest and movement will be assessed using a numerical rating scale (NRS) ( 0 means no pain” and 10 means the worst possible pain”). Pain at rest will be assessed with the patient lying supine and pain with movement will be assessed when moving from the supine to an upright sitting position.;Nausea. Timepoint: 6,12,18,24 hour after surgery. Method of measurement: Patients will be asked to rate the severity of postoperative nausea using an 11-point numerical rating scale (NRS) from 0 to 10 (0: no nausea” to 10: worst nausea possible”). The number of vomiting episodes, if any during the 24-h study period, will be documented.;Pruritus. Timepoint: 6,12,18,24 hour after surgery. Method of measurement: Pruritus will be assessed using an 11-point NRS (0: no pruritus” to 10: worst pruritus possible”).

Secondary Outcome Measures

Name	Time	Method
Headache. Timepoint: 6,12,18,24 hour after surgery. Method of measurement: Patients will be asked to rate the severity of postoperative headache using an 11-point numerical rating scale (NRS) from 0 to 10 (0: no headache” to 10: worst headache possible”). The number of headache episodes, if any during the 24-h study period, will be documented.