Evaluation of curcumin effects on vascular disease in diabetic patients undergoing hemodialysis

Phase 2

• Conditions: Condition 1: Diabetes. Condition 2: End stage renal disease.; Type 2 diabetes mellitus; End stage renal disease; N18.6

• Registration Number: IRCT20200527047584N1
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 July 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

GFR Between 15-89
SBP between 140-160 and DBP between 90-100 mmHg
Not pregnant or lactating
no history of smoking or alcohol abuse
no underlying condition including cardiovascular diseases , cancer , autoimmune disorders and thyroid function abnormalities
not having underlying disease that causes proteinuria

Exclusion Criteria

underlying diseases that caused admission to hospital
High blood pressure
using Fluvoxamine or any kind of antioxidant drugs
Night worker

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Carotid-femoral pulse wave velocity. Timepoint: Before intervention and 24 weeks after intervention. Method of measurement: Color doppler ultrasound.;Carotid Intima-media thickness. Timepoint: Before intervention and 24 weeks after intervention. Method of measurement: Color doppler ultrasound.

Secondary Outcome Measures

Name	Time	Method
Hs-CRP level. Timepoint: before and 24 weeks after intervention. Method of measurement: Blood test.