Does ATP cause Annexin A5 targeting in the human forearm?

Phase 1

• Conditions: atherosclerosis; MedDRA version: 9.1Level: LLTClassification code 10003601Term: Atherosclerosis

• Registration Number: EUCTR2007-005893-29-NL
• Lead Sponsor: RUNMC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-10-19
• Last Update Posted: 21 December 2021

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Male
• Target Recruitment: 51

Inclusion Criteria

-Male
-Age 18-50 years
-Informed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

-History of any cardiovascular disease
-Hypertension (in supine position: systole > 140 mmHg, diastole > 90 mmHg)
-Diabetes mellitus (fasting glucose > 7.0 mmol/L or random glucose > 11.0 mmol/L)
-Hyperlipidaemia (fasting total cholesterol > 5.5 mmol/l or random cholesterol > 6.5mmol/L)
-Drug abuse
-Concomitant chronic use of medication
-Administration of radioactivity for research purposes during the last 5 years
-Participation to any drug-investigation during the previous 60 days as checked with VIP check according to CRCN standard procedures

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified