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Association Between Ghrelin and Butyrylcholinesterase in Patients With Acute Decompensated Heart Failure: A Cross-sectional Study

Not Applicable
Recruiting
Conditions
Acute heart failure
Registration Number
JPRN-UMIN000040647
Lead Sponsor
Osaka General Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

Patients with liver disorder Patients with past history of removal of stomach Patients who is taking rivastigmine or rikkunshito Patients with anorexia or severe obesity (BMI>35) Patients with endocrine disease

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Association between plasma ghrelin level and serum butyrylcholinesterase level
Secondary Outcome Measures
NameTimeMethod
1) Vital signs: blood pressure, heart rate, body weight 2) Blood biomarkers: Albumin, prealbumin, T-chol, LDL-chol, HDL-chol, TG, BNP, NT-proBNP, hs-tropI, high sensitive CRP 3) Transthoracic echocardiography: LVEF, LVDd/Ds, E/e', LAD, LVEDV, LVESV, LV mass, TAPSE, RVEF, LA volume 4) Cardiac MIBG imaging: H/M MIBG uptake ratio on the delayed images, washout rate of cardiac MIBG 5) Body composition (bioimpedance method) 6) Electrocardiogram 7) Appetite score
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