Butyrylcholinesterase activity as a risk factor of postoperative delirium in cardiosurgical patients

Completed

• Conditions: F05.8; Other delirium

• Registration Number: DRKS00017144
• Lead Sponsor: niversitätsklinik für Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie Klinikum Oldenburg AÖR

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-05-15
• Study Completion: 2019-05-23
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Cardiac surgery under general anaesthesia, informed consent, ability to perform brief cognitive test

Exclusion Criteria

Emergency patients, not being able to perform cognitive test, age < 60 yrs

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Is there a difference between pre- and postoperative activity of the plasma butyrylcholinesterase in cardio surgical patients?

Secondary Outcome Measures

Name	Time	Method
1. Is the activity of butyrylcholinesterase in the group of patients, who later develop delirium, already reduced pre-operatively, compared to those who do not?<br>2. Is delirium more frequent in patients, whose butyrylcholinesterase-activity decreases after surgery?<br>3. Can the pre- or postoperative activity of butyrylcholinesterase serve as a risk factor of delirium?<br>4. Are differences between patients being operated on with or without cardiopulmonary bypass?