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Intravenous versus subcutaneous immunoglobuline therapy in multifocal motor neuropathy

Conditions
subcutaneous immunoglobuline therapy Multifocal motor neuropathyIntravenous immunoglobuline therapyDutch: subcutane immunoglobuline Intraveneus immunoglobulineMultifocale motorische neuropathy
Registration Number
NL-OMON21709
Lead Sponsor
Department of neurologyAcademical Medical Centre, AmsterdamMeibergdreef 9, 1100 DD Amsterdam020-5669111
Brief Summary

The writing commettee will consist of F. Eftimov, I.N. van Schaik, R. de Haan and M. Vermeulen.

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
10
Inclusion Criteria

All adult patients (> 18 years) with signs and symptoms consistent with MMN that fulfill the EFNS/PNS criteria for definite MMN and are being treated with IVIg for at least 6 months at regular intervals of at most 6 weeks. Patients have to have stable disease for at least 6 months before inclusion.

Exclusion Criteria

1. Use of drugs which are known to cause motor neuropathy;
2. Patient and/or partner is/are unable to administer SCIg at home;
3. Other diseases known to cause neuropathy or to reduce mobility;
4. Diseases known to lead to severe handicap or death at short notice;
5. A known selective IgA deficiency with anti-IgA antibodies;
6. Refusal to give informed consent or withdrawal of previously given permission;
7. Legally incompetent adult

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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