Efficacy and safety of intra-articular botulinum toxin A versus corticosteroid injections in knee osteoarthritis: A randomised control trial

Phase 2

• Conditions: Knee osteoarthritis; Musculoskeletal - Osteoarthritis; Anaesthesiology - Pain management

• Registration Number: ACTRN12621001622897
• Lead Sponsor: Stephanie Babic

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-29
• Last Update Posted: 6 December 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1.Age more than or equal to 40 years.
2.Diagnosis of knee OA confirmed on clinical exam and radiologically by Kellgren-Lawrence Grading Scale (Grade III or IV);
3.Symptoms present for more than or equal to 6 months; and
4.Ability to understand and participate in the trial.

Exclusion Criteria

1.Age less than 40 years;
2.Any intra-articular injection within the past 12 months;
3.History of trauma to the knee within the past 12 months;
4.History of surgery to the knee within the past 12 months;
5.Neuromuscular disorders (for example, myasthenia gravis, Lambert-Eaton, amyotrophic lateral sclerosis et cetera);
6.Other knee arthropathy (for example, RA, gout et cetera);
7.Lower extremity dysfunction due to a neurological or medical cause (for example, due to a cerebrovascular accident or traumatic brain injury, diabetic neuropathy et cetera);
8.Serious coagulation disorders or anticoagulant use; and
9.Pregnancy or breastfeeding.

Study & Design

• Study Type: Interventional
• Study Design: Not specified