Intra-articular Botulinum Neurotoxin in Knee Osteoarthritis
Phase 2
- Conditions
- Knee osteoarthritis.Secondary osteoarthritis of other joints
- Registration Number
- IRCT20180416039323N1
- Lead Sponsor
- Artesh University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
age ?50
crepitation or morning stiffness < 30 min
radiographic presentation
clinical symptom > 3 months
Exclusion Criteria
Patient dissatisfaction
Other articular disease in knee joint
Surgical history in the joint
Fracture history in bones of knee
Corticosteroid knee injection in the last 2 weeks, hyalorunic acid injection or prolotherapy over the past year
Any intraarticular injection contraindication
Allergy to toxin
Severe knee joint effusion
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of pain intensity and functional improvement with Knee Injury and Osteoarthritis Outcome Score questionnaire. Timepoint: evaluation of pain intensity and functional improvement before and 1 month after botulinum toxin injection. Method of measurement: Knee Injury and Osteoarthritis Outcome Score questionnaire.
- Secondary Outcome Measures
Name Time Method