Evaluation of the efficacy of Dexmedetomidine as an Adjuvant to Articaine in Minor Maxillofacial Surgical Procedures
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 34
- 试验地点
- 1
研究概览
简要总结
This prospective clinical study aims to evaluate the effectiveness of adding dexmedetomidine to 4% articaine in patients undergoing minor oral and maxillofacial surgical procedures under local anesthesia. A total of 34 patients (ASA I and II) aged 20–45 years will be included and allocated to receive articaine with dexmedetomidine. The study will assess onset and duration of anesthesia, intraoperative pain using the Visual Analog Scale (VAS), hemodynamic parameters (heart rate, blood pressure, and oxygen saturation), sedation level, and time to first rescue analgesic. The objective is to determine whether dexmedetomidine improves anesthetic efficacy, prolongs analgesia, and maintains hemodynamic stability compared to conventional local anesthesia, thereby enhancing patient comfort and surgical outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged from 20-45 years
- •ASA Physical Status I and II
- •Patients requiring minor oral and maxillofacial surgical procedures such as: a.
- •Open reduction & internal fixation of parasymphysis/symphysis/body/angle fractures (which can be operated under LA) b.
- •Small cysts and tumors (which can be operated under LA) c.
- •Other minor surgical procedures (which can be operated under LA) Deeply impacted mandibular 3rd molars ( Position C – WHARFE Assessment) Impacted canines.
排除标准
- •Known allergy to articaine or dexmedetomidine
- •Pregnant or lactating women
- •Patients with bradycardia, hypotension, cardiac abnormalities
- •Patients not willing to provide written informed consent.
研究者
Guntuboina Sree Varsha
Sibar institute of dental sciences