Study on clinical efficacy of combined traditional Chinese and Western medicine in treating acute pancreatitis

Phase 1

Recruiting

• Conditions: Acute pancreatitis

• Registration Number: ITMCTR2000003894
• Lead Sponsor: Shanghai General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients meeting the diagnostic criteria of acute pancreatitis: according to the 2012 Atlanta classification and definition revision international consensus, the diagnosis of acute pancreatitis needs 2 of the following three characteristics:
(1) Abdominal pain is consistent with the characteristics of acute pancreatitis (persistent and severe upper abdominal pain often radiates to the back);
(2) The activity of serum lipase (or amylase) was at least 3 times higher than the normal upper limit;
(3) Enhanced CT or infrequent magnetic resonance imaging (MRI) or abdominal ultrasonography revealed characteristic changes in acute pancreatitis.
2. Patients admitted within 72 hours after onset
3. The age of the patients is 18-75 years old
4. The patients whose family members (guardians) agreed to participate in the study, and signed informed consent and agreed to participate in the study.

Exclusion Criteria

1. Patients with severe hypertension (systolic blood pressure greater than 180mmhg, or the average systolic blood pressure increased by more than 40mmhg) were not well controlled under the condition of drug treatment;
2. Patients with severe respiratory, cardiovascular, digestive and hematological diseases, as well as psychiatric and infectious diseases;
3. Patients with serious illness who need non medical treatment such as surgery and peritoneal lavage;
4. Patients with advanced tumor;
5. Patients with chronic renal failure caused by organic kidney disease;
6. Patients who were enrolled in other clinical trials 3 months before onset of disease;
7. Pregnant or lactating women.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CRP;;SIRS;Local complications;Pass score;APACHE II;hospital stay;TNF-a;ICU occupancy rate;systemic complications;IL-6;