跳至主要内容
临床试验/NCT04220879
NCT04220879Unknown不适用

Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucoma

Zhongshan Ophthalmic Center, Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2019年11月25日最近更新:
适应症

试验速览

阶段
不适用
入组人数
60
试验地点
1
主要终点
Choroidal vascularity parameter

研究概览

简要总结

In this retrospective observational study, we collected intraocular structure parameters of malignant glaucoma and primary angle closure glaucoma. Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography. To analyze the high risk factors and the possible pathogenesis of the disease and discuss the long-term effect of different treatment methods.

详细描述

Outcome Measures:

Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Other

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • (1) history of operation, (2) diagnosis of MG, and (3) eyes with clear optical media.

排除标准

  • (1)hypertension or diabetes and (2) diagnosis of ocular fundus diseases.

结局指标

主要结局

Choroidal vascularity parameter

时间窗: baseline

Choroidal vascularity parameter is a vessel ratio measured by optical coherence tomographic images

Trabecular ciliary process angle

时间窗: baseline

TCPA is measured with its apex at the scleral spur, one arm along the posterior corneal surface, and another arm along the most anterior surface of the ciliary body

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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