The efficacy and mechanisms of transcutaneous auricular vagus nerve stimulation on symptom in patients with IBS-C

Phase 1

Not yet recruiting

• Conditions: Constipation-dominant irritable bowel syndrome

• Registration Number: ITMCTR2000002986
• Lead Sponsor: Shanghai East Hospital Affiliated to Tongji University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-02-20

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Willing to sign informed consent;
2. Aged 18 to 75 years, regardless of gender;
3. Meets IBS-C Rome IV diagnostic criteria.

Exclusion Criteria

1. History of previous abdominal surgery related to IBS-C symptoms (except appendectomy);
2. Currently taking antidepressants, including tricyclic antidepressants and selective serotonin reuptake inhibitors;
3. Use of anticholinergics, antipsychotics or antispasmodics in the past 2 weeks;
4. Currently participating in another trial or in the past month;
5. Currently pregnant or planning to become pregnant;
6. Accompanied by severe heart, liver or kidney disease, or have diabetes;
7. Researchers do not consider it suitable for participants.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified