A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults

Not Applicable

Completed

Conditions: Nicotine Dependence
Nicotine Addiction
Vaping
Nicotine Vaping
Nicotine Use Disorder

Registration Number: NCT05897242

Lead Sponsor: Fred Hutchinson Cancer Center

Brief Summary: Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants. Despite the need for effective treatments to help these young users quit, very few treatments targeting any type of tobacco use among young adults have been evaluated, particularly for young adults who vape and have unique treatment needs. To address these needs, this trial will evaluate a digital program for young adult e-cigarette users at all stages of readiness to quit called ACT on Vaping.

Detailed Description: OUTLINE:

Participants are randomized to 1 of 2 arms.

ARM I: Participants use the ACT on Vaping smartphone app and text messaging program and receive incentivized text messages assessing their vaping status.

ARM II: Participants receive incentivized text messages check-ins assessing their vaping status.

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 61

Inclusion Criteria

Age 18-30.
Current weekly user of e-cigarette product(s).
Owns an Android phone or iPhone.
Has an email address.
United States (US) resident, with a US mailing address.
Willing to complete all study procedures.

Exclusion Criteria

Currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (note: use of these treatments is allowable during trial participation).
Member of the same household as another research participant.

Study & Design

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Percentage of Participants With a 24-hour Quit Attempt	At 3 months post-randomization	Making a 24-hour quit attempt between baseline and 3-month follow-up was assessed via self-report at the 3-month follow-up survey. The percentage of participants with self-reported 24-hour quit attempts is evaluated descriptively.
Cotinine-confirmed 30-day Point Prevalence Abstinence From All Nicotine and Tobacco	At 3 months post-randomization	Complete case, self-reported 30-day abstinence from all nicotine and tobacco products at 3 months, confirmed via saliva cotinine testing. Differences were evaluated descriptively.
Overall Treatment Satisfaction Rating	At 3 months post-randomization	We calculated descriptive statistics (mean, standard deviation) for the primary acceptability benchmark of overall satisfaction averaging at least 3.5 on a 1-5 Likert-type scale within the ACT on Vaping arm only. Overall satisfaction was assessed with a 5-point Likert-type item on the 3-month follow-up survey, with response options ranging from (1) "not at all" to (5) "very much." The ACT on Vaping benchmark average of 3.5 falls between ratings of 3="somewhat" and 4="mostly." Higher values are associated with a higher level of satisfaction.
Change in Readiness to Quit	From baseline to 3 months post-randomization	Will evaluate differences of Contemplation Ladder scores. The 1-item Contemplation Ladder, scores range from 0-10, was used to assess readiness to quit using e-cigarettes. The higher the score, the more ready the person is to make a change. The anchor for the cut-off score of 5, indicating high vs. low quit readiness, is "Think I should quit but not quite ready."

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Fred Hutch/University of Washington Cancer Consortium
🇺🇸
Seattle, Washington, United States
Fred Hutch/University of Washington Cancer Consortium
🇺🇸Seattle, Washington, United States