Comparison of Magnesium sulphate adjuvant Perineurally vs intravenously to levobupivacaine in usg guided supraclavicular block

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/12/048238
• Lead Sponsor: Chettinad Academy of Research and Education

Brief Summary

To compare analgesic efficacy between perineural and intravenous magnesium sulphate as an adjuvant to levobupivacaine in ultrasound-guided supraclavicular brachial plexus block



Group 1 perineural magnesium sulphate – patient will receive 0.5% levobupivacaine (24.5ml) with 250 mg of magnesium sulphate (0.5ml) total volume of 25ml in usg guided supraclavicular nerve block

Group 2 intravenous magnesium sulphate – patient will receive 0.5% levobupivacaine  (24.5ml) with 0.5ml NS total volume of 25ml in usg guided supraclavicular nerve block plus 30 mg/kg iv magnesium sulphate



Primary objective

•To compare the duration of analgesia

Secondary objective

•To compare the onset of sensory and motor block

•To compare the requirement of rescue analgesic in the postoperative period

•To compare the side effects (if any)

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-12-14
• Study Start: 2023-12-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• 1. Age between 18.
• 60 years 2.Both sexes3. ASA Classes I,II and III patients 4. Patients posted for upper limb surgery below shoulder.

Exclusion Criteria

• 1.Patient refusal2.
• Coagulopathy3.
• History of allergy to local anesthetics4.
• Infection at the site of block5.
• Neurodeficit involving brachial plexus6.
• Pregnant women7.
• Patients with psychiatric behavior8.
• ASA Class IV patients 9.Obese patients BMI>35kg/m2.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of analgesia	2 years

Secondary Outcome Measures

Name	Time	Method
• To compare the onset of sensory and motor block	•To compare the requirement of rescue analgesic in the postoperative period

Trial Locations

Locations (1)

Chettinad Hospital and Research Institute; 🇮🇳 Chennai, TAMIL NADU, India

Chettinad Hospital and Research Institute

🇮🇳Chennai, TAMIL NADU, India

Dr Koushallya Sri S

Principal investigator

7299224444

akskoush@gmail.com