To compare the effectiveness of intravenous magnesium sulphate and paracetamol in reducing the pain after surgery in patients undergoing Total abdominal hysterectomy

Phase 4

Not yet recruiting

• Conditions: Abnormal uterine and vaginal bleeding, unspecified, (2) ICD-10 Condition: N926||Irregular menstruation, unspecified,

• Registration Number: CTRI/2023/07/055582
• Lead Sponsor: ANU ELSA BOBBY

Brief Summary

This is a study to compare the post operative analgesic effect of intravenous magnesium sulphate and paracetamol in patients undergoing total abdominal hysterectomy under Sub arachnoid block. This surgery is associated with severe post operative pain and patients require analgesics including opioids. This study is conducted to find out if the analgesic requirement has reduced in patients receiving these drugs.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-08
• Last Update Posted: 2023-07-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 39

Inclusion Criteria

1.ASA grade 1 and 2 patients.

Exclusion Criteria

1.Emergency surgeries 2.BMI > 40kg/m2 3.Patients with known allergy to the drugs used in study 4.Patients with renal insufficiency 5.Neuromuscular diseases 6.Hepatic dysfunction 7.Cardiac disease 8.Previous oncological surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score in both the group	0hr, 4hr, 8 hr, 12hr , 16hr, 20 hr , 24hr

Secondary Outcome Measures

Name	Time	Method
•Total analgesic requirement in the two groups in first 24 hours	•Time (in minutes) to request first analgesic in both groups

Trial Locations

Locations (1)

Pushpagiri Medical College and Research Centre; 🇮🇳 Pathanamthitta, KERALA, India

Pushpagiri Medical College and Research Centre

🇮🇳Pathanamthitta, KERALA, India

DR ANU ELSA BOBBY

Principal investigator

8111952093

anuelsa96@gmail.com