Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

Not Applicable

Completed

• Conditions: Thyroid Neoplasms
• Interventions: Drug: Normal saline; Drug: Magnesium Sulfate

• Registration Number: NCT02826746
• Lead Sponsor: Ajou University School of Medicine

Brief Summary

The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07
• Study First Submitted: 2016-07-06
• Study First Submitted QC: 2016-07-07
• Study First Posted: 2016-07-11
• Primary Completion: 2019-03
• Study Completion: 2019-03
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-03
• Last Update Posted: 2019-04-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Thyroidectomy

Exclusion Criteria

• Allergy to magnesium
• Chronic pain
• Chronic opioid use
• Chronic NSAID use
• Renal dysfunction
• Liver dysfunction
• Cardiac arrythmia
• Seizure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	Normal saline	intravenous administration of normal saline
Magnesium group	Magnesium Sulfate	intravenous administration of Magnesium Sulfate

Primary Outcome Measures

Name	Time	Method
Throat pain	Up to 48 hours after surgery end	pain assessment using visual analog scale

Secondary Outcome Measures

Name	Time	Method
Fentanyl dose in recovery room	Up to 30 minutes after surgery end

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine; 🇰🇷 Suwon, Seoum, Korea, Republic of