The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation

Phase 3

Completed

• Conditions: Increased Intra Ocular Pressure (IOP)
• Interventions: Drug: Magnesium Sulfate; Drug: normal saline

• Registration Number: NCT01241175
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non ocular surgery

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-03
• Study First Submitted: 2010-11-15
• Study First Submitted QC: 2010-11-15
• Last Update Submitted: 2010-11-15
• Study First Posted: 2010-11-16
• Last Update Posted: 2010-11-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• 18 to 38 years old
• ASA I
• scheduled for elective ENT ambulatory surgeries under general anesthesia

Exclusion Criteria

• specific major hepatic, renal and cardio-vascular disease
• known to have allergic reaction to magnesium sulphate or other drugs , -hypermagnesemia
• hypocalcemia
• anuria
• heart block
• pregnancy
• any degree of renal insufficiency
• digitalised patients
• positive history of glaucoma or intra ocular hypertension
• refused to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
magnesium sulfate	Magnesium Sulfate	-
normal saline	normal saline	-

Primary Outcome Measures

Name	Time	Method
Intra ocular pressure

Secondary Outcome Measures

Name	Time	Method
blood pressure,heart rate

Trial Locations

Locations (1)

Shiraz University of Medical Sciences; 🇮🇷 Shiraz, Fars, Iran, Islamic Republic of