Studies of Kidney Transplant Outcome

Completed

• Conditions: Transplant Recipient (Kidney); Thymoglobulin; Steroid-Free Maintenance Immunosuppression; Post-Transplant Infections
• Interventions: Drug: Steroid-Free Maintenance Immunosuppression; Other: Infection After Kidney Transplantation; Drug: Evaluation of the DGF nomogram in Thymoglobulin

• Registration Number: NCT01277770
• Lead Sponsor: University of Minnesota

Brief Summary

The purpose of this study is to improve outcome for kidney transplant recipients. There has not been commensurate improvement in medium and long-term outcomes. Ongoing clinical research is necessary to improve transplant outcomes.

Detailed Description

This study is looking at information already collected of transplant outcomes (short, medium and long-term complications and quality of life). This will specifically look at:

1. 10 year follow-up of steroid-free maintenance immunosuppression

2. A cross-sectional study of infection after kidney transplantation (with emphasis on infection in steroid-free recipients

3. An evaluation of the Delayed Graft Function (DGF) nomogram in Thymoglobulin treated recipients at the University of Minnesota

Study Timeline

• Study Start: 2009-05
• Study First Submitted: 2010-08-19
• Study First Submitted QC: 2011-01-13
• Study First Posted: 2011-01-17
• Status Verified: 2019-05
• Primary Completion: 2019-05-06
• Study Completion: 2019-05-06
• Last Update Submitted: 2019-05-14
• Last Update Posted: 2019-05-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 7500

Inclusion Criteria

• Kidney Transplant Recipient at the University of Minnesota
• Kidney Transplant Recipients on steroid-free maintenance immunosuppression

Exclusion Criteria

• Non-kidney transplant patients at the University of Minnesota

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Kidney Transplant Recipients	Steroid-Free Maintenance Immunosuppression	Kidney Transplant Recipients at the University of Minnesota since 1984. The study looks at a 10 year followup of steroid-free maintenance immunosuppression, post-transplant infections and evaluation of the DGF nomogram in Thymoglobulin on patients at the University of Minnesota.
Kidney Transplant Recipients	Evaluation of the DGF nomogram in Thymoglobulin	Kidney Transplant Recipients at the University of Minnesota since 1984. The study looks at a 10 year followup of steroid-free maintenance immunosuppression, post-transplant infections and evaluation of the DGF nomogram in Thymoglobulin on patients at the University of Minnesota.
Kidney Transplant Recipients	Infection After Kidney Transplantation	Kidney Transplant Recipients at the University of Minnesota since 1984. The study looks at a 10 year followup of steroid-free maintenance immunosuppression, post-transplant infections and evaluation of the DGF nomogram in Thymoglobulin on patients at the University of Minnesota.

Primary Outcome Measures

Name	Time	Method
Data Analysis	10 year followup	All studies are analyses from the Transplant Outcomes Database. Recipients have signed consent to have medical information entered into the database for these analyses. The database contains information on short, medium and long-term results.

Trial Locations

Locations (1)

University Of Minnesota; 🇺🇸 Minneapolis, Minnesota, United States