PROVIDING OXYGEN BY NASAL PRONGS AT FLOW MORE THAN 2 LITRES PER MINUTE VERSUS PROVIDING OXYGEN WITH NASAL PRONGS USING CPAP DEVICE IN CHILDREN WITH DIFFICULTY IN BREATHING.

Not yet recruiting

• Conditions: Unspecified acute lower respiratory infection,

• Registration Number: CTRI/2023/05/052491
• Lead Sponsor: Motukuri Sesha Sarat Chandra

Brief Summary

To compare out comes of humidified high flow nasal cannula versus continuous positive airway pressure in children of respiratory distress presenting to tertiary care hospital Aurangabad.

Primary objective:

To compare success rate/failure rate between HFNC & CPAP treatment group.

(success is defined if patient is started on non-invasive ventilation and does not require invasive ventilation throughout the course,

Failure is defined as if patient requiring invasive ventilation after non-invasive ventilation)

Secondary objective:

To study complications like abdominal distension, issue of feeding intolerance, nasal mucosal injury, discharge on oxygen supplementation & prolonged ICU stay.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-15
• Last Update Posted: 2023-10-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

All children from 1 month to 18 years having Respiratory distress.

Exclusion Criteria

Intubation on admission Children with congenital heart diseases Children with neurological diseases Covid positive patients Children with chest wall deformity.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Success & failure rate of the intervention done. Success is defined as patient not requiring invasive ventilation after the intervention. Failure is defined as patient requiring invasive ventilation.	Assessed from time of admission till 72 hours of intervention

Secondary Outcome Measures

Name	Time	Method
Document complications like abdominal distension, feeding intolerance, nasal mucosal injury, prolonged ICU stay and discharge on oxygen supplementation	After starting intervention till discharge or death

Trial Locations

Locations (1)

MGM Medical College; 🇮🇳 Aurangabad, MAHARASHTRA, India

MGM Medical College

🇮🇳Aurangabad, MAHARASHTRA, India

Motukuri Sesha Sarat Chandra

Principal investigator

8096692642

sc73010@gmail.com