Epstein-Barr Detection in Oral Cancer

Completed

• Conditions: Oral Cancer

• Registration Number: NCT01039272
• Lead Sponsor: UPECLIN HC FM Botucatu Unesp

Brief Summary

The aim of this study is to analyze oral squamous cell carcinoma and healthy oral mucosa for the possible presence of Epstein-Barr virus (EBV).

Detailed Description

Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

Study Timeline

• Study Start: 2008-03
• Primary Completion: 2008-04
• Study First Submitted: 2009-12-22
• Study First Submitted QC: 2009-12-22
• Study First Posted: 2009-12-24
• Status Verified: 2015-06
• Study Completion: 2015-06
• Last Update Submitted: 2015-06-24
• Last Update Posted: 2015-06-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• patients of Oral Cancer Centre - UNESP/Araçatuba - SP
• with oral squamous cell carcinoma

Exclusion Criteria

• without oral squamous cell carcinoma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
presence of EBV	1 hour	Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

Trial Locations

Locations (1)

Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP; 🇧🇷 Araçatuba, São Paulo, Brazil