Effect of a Low-glycemic-load and Milk-free Diet on Acne Severity
Not Applicable
- Conditions
- Acne Vulgaris
- Interventions
- Other: Low-glycemic-load and milk-free diet
- Registration Number
- NCT01969175
- Lead Sponsor
- Parc Taulí Hospital Universitari
- Brief Summary
The objective of this study is to assess the effect of a low-glycemic-load and milk-free diet on acne severity.
IGF-1 and a phosphorylated product of the mTORC pathway (p70S6K) will be assessed in both groups to explore the mTORC signaling pathway, which is thought to be related to clinical improvement in previous studies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Mild, moderate or severe acne (GAGS score 15-44)
- Age: 14-20 years old
- Presence of acne for at least 2 months
Exclusion Criteria
- Diabetes
- Polycystic ovary syndrome
- Use of hormonal contraceptives
- Previous use of oral retinoids
- Use of oral antibiotics or topical antibacterial or retinoid agents in the last 2 months
- Use of medications known to cause or exacerbate acne including lithium, oral or injected retinoids, some anticonvulsant drugs, medications containing iodides or bromides
- Drug or alcohol abuse.
- Active smokers
- Anticipated difficulty attending visits or fear of blood draws
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Intervention Diet Low-glycemic-load and milk-free diet -
- Primary Outcome Measures
Name Time Method GAGS Acne severity scale 13 weeks
- Secondary Outcome Measures
Name Time Method Serum insulin like growth factor 1 (IGF-1) 13 weeks Diet acceptability and adherence 13 weeks p70S6K 13 weeks A phosphorylated product of mTORC signaling pathway
Trial Locations
- Locations (1)
Hospital Parc Taulí
🇪🇸Sabadell, Barcelona, Spain