Anti diabetic effect and safety of turmeric powder in type 2 diabetes
- Conditions
- Health Condition 1: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2019/02/017474
- Lead Sponsor
- Academic trial JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients with type 2 diabetes mellitus diagnosed within the past 3 months to 10 years, on a stable dose of metformin and (or) sulfonylureas, for at least past 3 months
2. HbA1c <8%
1. Liver dysfunction (AST, ALT > 2 times the upper limit of normal)
2. Renal dysfunction (GFR <60 ml/min)
3. Patient with concurrent illnesses like CAD(Coronary Artery Disease), CVA( cerebrovascular accidents), PVD(Peripheral Vascular Disease), CKD( Chronic Kidney Disease)
4. Pregnant women or lactating mother
5. women in the reproductive age group not practising contraceptive measures.
6. Patients who had participated in other trials in the past three months.
7. Those on other herbal medications.
8. Chronic alcoholics
9. Patients with any active infections including diabetic foot infection
10. History of allergy to any drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the change in glycemic status (HbA1C, fasting blood glucose, post prandial blood glucose) from baseline to end of treatment (3 months) between oral Curcuma longa and placebo in patients with type 2 diabetes mellitusTimepoint: 3
- Secondary Outcome Measures
Name Time Method i.To compare the change in OGTT based indices (HOMA-IR, Matsuda index) of insulin sensitivity and resistance from baseline to end of treatment (3 months) between oral Curcuma longa and placebo in patients with type <br/ ><br>ii. to compare changes in Adiponectin and Malondialdehyde (MDA) levels, frequency of adverse drug reactions between two groupsTimepoint: 3