comparison of curcuma with meloxicam in knee osteoarthritis pain relief

Phase 3

Recruiting

• Conditions: knee osteoarthritis.; Unspecified osteoarthritis, unspecified site; M19.90

• Registration Number: IRCT20220513054837N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

completing and signing a consent form
having symptoms of knee osteoarthritis in at least one recent month
age between 40 and 60
lack of the presence of any other disease around the affected limb

Exclusion Criteria

having diabetes
having diseases such as Rheumatism, gout, collagen vascular and lupus
having accompanying radiculopathy
history of trauma, fracture and injury to the affected joint, nerve damage and neuropathies
history of knee replacement on the affected side
history of allergies to drugs used in the study
history of significant heart, kidney, liver and lung disorders
pregnant and lactating women
BMI above 42
having brucellosis
history of injection in the affected joint or in addition in the last 3 months
inability to communicating and completing questionnaires
patients taking anticoagulants
cancer patients
history or gastrointestinal disorders and stomach problems
consuming warfarin and ticlopidine and aspirin
uncontrolled hypertension
very severe osteoarthritis of the knee based on radiology

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain rate based on the score obtained from the Visual Analog Scale questionnaire in the study. Timepoint: before and after starting treatment in second , forth and fifth weeks. Method of measurement: Filling in the questionnaire VAS by the patient and reading the questionnaire information.;Knee disability based on the score obtained from the Oxford knee Scale in the study. Timepoint: before and after starting treatment in second , forth and fifth weeks. Method of measurement: Filling in the questionnaire OKS by the patient and reading the questionnaire information.;Morning stiffness based on the score obtained from the Western Ontario and McMaster Universities Arthritis Index in the study. Timepoint: before and after starting treatment in second , forth and fifth weeks. Method of measurement: Filling in the questionnaire WOMAC by the patient and reading the questionnaire information.