Evaluation of Curcumin effevtiveness in prophylaxis of renal toxicity
Phase 3
- Conditions
- ephrotoxicity caused by cisplatin injection.
- Registration Number
- IRCT20181208041882N4
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Patients 18 to 80 years old to get started chemotherapy with Cisplatin
The patient satisfaction
Exclusion Criteria
Active infection
Heart failure
Liver failure
Taking other nephrotoxic drugs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement Mg Urinary Random. Timepoint: Two days before and two days after Cisplatin injection. Method of measurement: Laboratory data.;Measurement Ca Urinary Random. Timepoint: two Days before and two Days after Cisplatin injection. Method of measurement: Laboratory data.;Measurement Na Urinary Random. Timepoint: two Days before and two Days after Cisplatin injection. Method of measurement: Laboratory data.;Measurement K Urinary Random. Timepoint: two Days before and two Days after Cisplatin injection. Method of measurement: Laboratory data.;Measurement of urinary protein NGAL (Neutrophil gelatinase-associated lipocalin) . In acute kidney damage, the protein is released from the damaged kidney cells after 2 hours and enters the urine. Timepoint: Measurement of urinary NGAL two days before and two days after cisplatin injection. Method of measurement: Based on the ELISA diagnostic kit.
- Secondary Outcome Measures
Name Time Method