Curcumin efficacy on oral lichen planus
Phase 2
- Conditions
- ichen planus.Lichen planus
- Registration Number
- IRCT2015121425498N1
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Patients with clinical signs of erosive and atrophic OLP confirmed by clinical or histopathological examination were included in our study.
The exclusion criteria: pregnancy; lactation; current use of anticoagulants or antiplatelet agents; currant orthodontic treatment; history of gastric ulcers; duodenal ulcers; gallstones; hepatic diseases; any existing malignancy or viral infection in mouth; receiving any topical treatment for OLP in the past 2 weeks or any systemic treatment for OLP in the past 4 weeks; use of azathioprine, cyclosporine or receiving PUVA, UVA or UVB in the last month; a history of allergy to corticosteroids or curcumin.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ichen planus improvement. Timepoint: On days 14 and 28. Method of measurement: Thongprasom index.
- Secondary Outcome Measures
Name Time Method Pain and burning sensation. Timepoint: On days 14 and 28. Method of measurement: Visual analogue scale.