MedPath

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Phase 3
Active, not recruiting
Conditions
Anal Basaloid Carcinoma
Anal Canal Cloacogenic Carcinoma
Anal Margin Squamous Cell Carcinoma
Stage IIB Anal Cancer AJCC v8
Stage III Anal Cancer AJCC v8
Interventions
Procedure: Biopsy Procedure
Procedure: Biospecimen Collection
Procedure: Colonoscopy
Procedure: Computed Tomography
Procedure: Digital Rectal Examination
Procedure: High Resolution Anoscopy
Procedure: Magnetic Resonance Imaging
Other: Patient Observation
Procedure: Proctoscopy
Procedure: Sigmoidoscopy
Procedure: X-Ray Imaging
Registration Number
NCT03233711
Lead Sponsor
National Cancer Institute (NCI)
Brief Summary

This phase III trial investigates how well nivolumab after combined modality therapy works in treating patients with high risk stage II-IIIB anal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Detailed Description

PRIMARY OBJECTIVE:

I. To evaluate whether therapy with nivolumab following combined modality therapy (CMT) improves disease-free survival (DFS) compared with observation in patients with high risk anal carcinoma.

SECONDARY OBJECTIVES:

I. To compare nivolumab following combined modality therapy (CMT) with observation in patients with high risk anal carcinoma with regard to:

Ia. Objective response rate (complete \[CR\] and partial \[PR\]), stable disease and progression.

Ib. Severe toxicity interval. Ic. Colostomy-free survival. Id. Overall survival. Ie. Toxicity.

OUTLINE: Patients who received standard CMT are randomized to 1 of 2 arms.

ARM A: Patients receive nivolumab intravenously (IV) while on study.

ARM B: Patients undergo observation while on study

Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, computed tomography (CT) scan, magnetic resonance imaging (MRI), biopsy and blood sample collection throughout the study.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
344
Inclusion Criteria
  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Age >= 18 years

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients must have histologically proven stage IIB (T3N0M0 only), IIIA (T2N1M0), IIIB (T4N0M0), or IIIC (T3N1M0, T4N1M0) invasive squamous cell carcinoma of the anus or anorectum, according to the American Joint Committee on Cancer (AJCC) 8th edition; this may include tumors of non-keratinizing histology such as basaloid, transitional cell, or cloacogenic histology; individuals with squamous cell carcinoma of the anal margin are eligible if there is evidence of extension of the primary tumor into the anal canal

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients must have Eastern Cooperative Oncology Group (ECOG) performance status of 0-2

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients must have hemoglobin levels of > 9 g/dL (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patient must have a platelet count of > 100,000/mm^3 (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patient's absolute neutrophil count (ANC) level must be > 1500/mm^3 (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Serum creatinine must be =< 1.5 X upper limit of normal (ULN) (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Total bilirubin must be < 2 X ULN (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase [SGPT]) =< 2.5 X institutional upper limit of normal (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Albumin >= 3.0 g/dL (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients known to be human immunodeficiency virus (HIV)+ are permitted; patients with CD4 > 200 and serum HIV viral load of < 200 copies/mm^3 are eligible, and in addition:

    • Participants must be purified protein derivative (PPD) negative; alternatively, the QuantiFERON-tuberculosis (TB) Gold In-Tube (QFT-GIT) assay (Cellestis Limited, Carnegie, Australia) can be used; an individual is considered positive for M. tuberculosis infection if the IFN-gamma response to TB antigens is above the test cut-off (after subtracting the background IFN-gamma response in the negative control); the result must be obtained within 20 weeks prior to enrollment; PPD positive (or Quantiferon assay positive) participants are permitted if prophylaxis has been completed prior to enrollment
    • No history of acquired immune deficiency syndrome (AIDS)-related complications within past year other than a history of low CD4+ T-cell count > 200/mm^3 prior to initiation of combination antiretroviral therapy; on study CD4+ T-cell count may not be informative due to chemoradiotherapy and should not be used as an exclusion criterion if low
    • Patient must be healthy on the basis of HIV disease with high likelihood of near normal life span were it not for the anal cancer
    • Participants MUST receive appropriate care and treatment for HIV infection, including antiretroviral medications when clinically indicated, and should be under the care of a physician experienced in HIV management; participants will be eligible regardless of antiretroviral medication (including no antiretroviral medication) provided there is no intention to initiate therapy or the regimen has been stable for at least 4 weeks with no intention to change the regimen within 12 weeks following enrollment
    • Patient must have =< grade 2 diarrhea (participants with grade 1 diarrhea are eligible provided stool for ova/parasites and stool cryptosporidium studies are negative;
    • NOTE: HIV testing is not required for eligibility
  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: For patients registering prior to start of chemoradiotherapy, baseline scans must have been completed within 4 weeks prior to registration

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Women of child bearing potential and sexually active males must use accepted and effective method(s) of contraception and/or abstain from sexual intercourse while on protocol treatment and for at least 5 months after the last dose of nivolumab (for female patients) and for at least 7 months after the last dose of nivolumab (for male patients)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Any surgery must have been completed >= 4 weeks prior to starting study treatment

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: No uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: No prior treatment with an immune checkpoint inhibitor (anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CTLA4 monoclonal antibody)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: No patients with immunodeficiency or receiving systemic steroid therapy equivalent to > 10 mg prednisone per day or any other form of immunosuppressive therapy within 7 days prior to Step 1 registration; topical corticosteroid or occasional inhaled corticosteroids are allowed

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: No live vaccines within 30 days prior to registration; examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, yellow fever, rabies, BCG, and typhoid (oral) vaccine; seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are live attenuated vaccines and are not allowed

    • NOTE: no live vaccines may be administered while participating in the trial
  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Previously irradiated patients (Arm S) must have received radiation per National Comprehensive Cancer Network guidelines; radiation therapy delivered on protocol (Arm T) will be reviewed

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients will be registered within 63 days following completion of standard chemoradiation for anal cancer; standard chemoradiation therapy is as defined

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must have histologically proven stage IIB (T3N0M0 only), IIIA (T2N1M0), IIIB (T4N0M0), or IIIC (T3N1M0, T4N1M0) invasive squamous cell carcinoma of the anus or anorectum, according to the AJCC 8th edition; this may include tumors of non-keratinizing histology such as basaloid, transitional cell, or cloacogenic histology; individuals with squamous cell carcinoma of the anal margin are eligible if there is evidence of extension of the primary tumor into the anal canal

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must have received at least 54 gray (Gy) of radiation to the PTVp (primary) and 45 Gy to PTVn (elective nodal region) for the treatment of the anal cancer

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must have ECOG performance status of 0-2

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must have hemoglobin levels of > 10 g/dL (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patient must have a platelet count of > 100,000/mm^3 (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patient's ANC level must be > 1500/mm^3 (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Serum creatinine must be =< 1.5 X ULN (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Total bilirubin must be < 2 X ULN (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: AST (SGOT)/ALT (SGPT) =< 2.5 X institutional upper limit of normal (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Albumin >= 3.0 g/dL (within 2 weeks prior to registration)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients known to be human immunodeficiency virus (HIV)+ patients with CD4 > 200 and serum HIV viral load of < 200 copies/mm^3 are eligible; in addition:

    • Participants must be PPD negative; alternatively, the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay (Cellestis Limited, Carnegie, Australia) can be used; an individual is considered positive for M. tuberculosis infection if the IFN-gamma response to TB antigens is above the test cut-off (after subtracting the background IFN-gamma response in the negative control); the result must be obtained within 20 weeks prior to enrollment; PPD positive (or Quantiferon assay positive) participants are permitted if prophylaxis has been completed prior to enrollment; NOTE: If patient completed chemoradiation on Step 1, PPD testing does not need to be performed again
    • No history of AIDS-related complications within past year other than a history of low CD4+ T-cell count > 200/mm^3 prior to initiation of combination antiretroviral therapy; on study CD4+ T-cell count may not be informative due to chemoradiotherapy should not be used as an exclusion criterion if low
    • Patient must be healthy on the basis of HIV disease with high likelihood of near normal life span were it not for the anal cancer
    • Participants MUST receive appropriate care and treatment for HIV infection, including antiretroviral medications when clinically indicated, and should be under the care of a physician experienced in HIV management; participants will be eligible regardless of antiretroviral medication (including no antiretroviral medication) provided there is no intention to initiate therapy or the regimen has been stable for at least 4 weeks with no intention to change the regimen within 12 weeks following enrollment
    • Patient must have =< grade 2 diarrhea (participants with grade 1 diarrhea are eligible provided stool for ova/parasites and stool cryptosporidium studies are negative)
    • NOTE: HIV testing is not required for eligibility
  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Scans done within 4 weeks of randomization to Step 2

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patient must have recovered from all toxicities associated with chemoradiotherapy for anal cancer, to grade =< 1 with the exception of alopecia

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Women of child bearing potential and sexually active males must use accepted and effective method(s) of contraception and/or abstain from sexual intercourse while on protocol treatment and for at least 5 months after the last dose of nivolumab (for female patients) and for at least 7 months after the last dose of nivolumab (for male patients)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: No uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: No prior treatment with an immune checkpoint inhibitor (anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CTLA4 monoclonal antibody)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: No patients with immunodeficiency or receiving systemic steroid therapy equivalent to > 10 mg prednisone per day or any other form of immunosuppressive therapy within 7 days prior to the first dose of study medication; topical corticosteroid or occasional inhaled corticosteroids are allowed

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: No live vaccines within 30 days prior to the first dose of trial treatment and while participating in the trial; examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, yellow fever, rabies, BCG, and typhoid (oral) vaccine; seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are live attenuated vaccines and are not allowed

Exclusion Criteria
  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: For patients registering to Arm T, patients must not have received prior chemoradiotherapy for anal cancer

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients with an allogenic bone marrow/stem, cell or solid organ transplant are excluded

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Women MUST NOT be pregnant or breast-feeding due to the potential teratogenic harm or abortifacient effects to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used; all patients must also not expect to conceive or father children from study registration and throughout their time on study treatment; for female patients this must continue until at least 5 months after the last dose of nivolumab and for male patients until at least 7 months after the last dose of nivolumab; all females of child bearing potential must have a serum or urine pregnancy test to rule out pregnancy within 2 weeks prior to registration; a female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy, or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients will be excluded if they have a T1 or M1, and T2N0 cancer

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients must not have had prior potentially curative surgery (abdominal, peritoneal resection) for carcinoma of the anus

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Participants may not be receiving any other standard anti-cancer therapy or experimental agent concurrently with the study drugs

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Individuals with a history of a different malignancy are ineligible except if they have been disease-free for at least 2 years and are deemed by the investigator to be at low risk for recurrence; individuals with the following cancers are eligible if diagnosed and treated within the past 5 years: cervical cancer in situ, and basal cell or squamous cell carcinoma of the skin

  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patient must not have active autoimmune disease in the past 2 years

    • NOTE: This does not include patients with autoimmune disease controlled by medication, such as hypothyroidism; this eligibility includes only patients with endocrine disease controlled by hormone replacement, e.g. hypothyroid, adrenal insufficiency, or diabetes mellitus (DM)
  • REGISTRATION TO STEP 1 ELIGIBILITY CRITERIA: Patients must not have known interstitial lung disease that is symptomatic or may interfere with the detection or management of suspected drug-related pulmonary toxicity

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients with an allogenic bone marrow/stem, cell or solid organ transplant are excluded

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Women MUST NOT be pregnant or breast-feeding due to the potential teratogenic harm or abortifacient effects to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used; all patients must also not expect to conceive or father children from study registration and throughout their time on study treatment; for female patients this must continue until at least 5 months after the last dose of nivolumab and for male patients until at least 7 months after the last dose of nivolumab; all females of child bearing potential must have a serum or urine pregnancy test to rule out pregnancy within 2 weeks prior to registration; a female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy, or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must not have had prior potentially curative surgery (abdominal, peritoneal resection) for carcinoma of the anus

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Participants may not be receiving any other standard anti-cancer therapy or experimental agent concurrently with the study drugs

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Individuals with a history of a different malignancy are ineligible except if they have been disease-free for at least 2 years and are deemed by the investigator to be at low risk for recurrence; individuals with the following cancers are eligible if diagnosed and treated within the past 5 years: cervical cancer in situ, and basal cell or squamous cell carcinoma of the skin

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patient must not have active autoimmune disease that has required systemic treatment in past 2 years

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must not have known interstitial lung disease that is symptomatic or may interfere with the detection or management of suspected drug-related pulmonary toxicity

  • REGISTRATION TO STEP 2 ELIGIBILITY CRITERIA: Patients must not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition to nivolumab

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm A (nivolumab)Biopsy ProcedurePatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)Biospecimen CollectionPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)Computed TomographyPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)Digital Rectal ExaminationPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)ColonoscopyPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)High Resolution AnoscopyPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)NivolumabPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)SigmoidoscopyPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)Magnetic Resonance ImagingPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)ProctoscopyPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm A (nivolumab)X-Ray ImagingPatients receive nivolumab while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)Biospecimen CollectionPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)ColonoscopyPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)Computed TomographyPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)Digital Rectal ExaminationPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)High Resolution AnoscopyPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)Magnetic Resonance ImagingPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)Patient ObservationPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)ProctoscopyPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)SigmoidoscopyPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Arm B (clinical observation)X-Ray ImagingPatients undergo observation while on study. Patients undergo sigmoidoscopy, colonoscopy or anoscopy, proctoscopy or digital rectal exam, x-ray, CT scan, MRI, biopsy and blood sample collection throughout the study.
Primary Outcome Measures
NameTimeMethod
Disease free survivalUp to 5 years

Will be defined as the occurrence of progression of local disease, distant metastases, second primary or death from the date of randomization.

Secondary Outcome Measures
NameTimeMethod
Objective response rateUp to 5 years

Will be defined by complete and partial response.

Overall survivalUp to 5 years
Incidence of toxicitiesUp to 5 years

Will be assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0.

Colostomy-free survivalUp to 5 years
Severe toxicity intervalThe time between randomization and the occurrence of late severe side effects (up to 5 years)

The following late side effects are considered as severe: any anal/rectal damage (ulcer, fistula, or perforation), rectal stenosis that required colostomy, skin ulceration, and severe fibrosis. This parameter estimates the probability of being free of late side effects for patients under loco-regional control.

Trial Locations

Locations (900)

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

University of Alabama at Birmingham Cancer Center

🇺🇸

Birmingham, Alabama, United States

Anchorage Associates in Radiation Medicine

🇺🇸

Anchorage, Alaska, United States

Anchorage Radiation Therapy Center

🇺🇸

Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Women's Cancer Care

🇺🇸

Anchorage, Alaska, United States

Anchorage Oncology Centre

🇺🇸

Anchorage, Alaska, United States

Katmai Oncology Group

🇺🇸

Anchorage, Alaska, United States

Providence Alaska Medical Center

🇺🇸

Anchorage, Alaska, United States

Fairbanks Memorial Hospital

🇺🇸

Fairbanks, Alaska, United States

CTCA at Western Regional Medical Center

🇺🇸

Goodyear, Arizona, United States

Kingman Regional Medical Center

🇺🇸

Kingman, Arizona, United States

Mayo Clinic Hospital in Arizona

🇺🇸

Phoenix, Arizona, United States

Mayo Clinic in Arizona

🇺🇸

Scottsdale, Arizona, United States

Mercy Hospital Fort Smith

🇺🇸

Fort Smith, Arkansas, United States

CHI Saint Vincent Cancer Center Hot Springs

🇺🇸

Hot Springs, Arkansas, United States

NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro

🇺🇸

Jonesboro, Arkansas, United States

University of Arkansas for Medical Sciences

🇺🇸

Little Rock, Arkansas, United States

Kaiser Permanente-Anaheim

🇺🇸

Anaheim, California, United States

Kaiser Permanente-Deer Valley Medical Center

🇺🇸

Antioch, California, United States

Mission Hope Medical Oncology - Arroyo Grande

🇺🇸

Arroyo Grande, California, United States

PCR Oncology

🇺🇸

Arroyo Grande, California, United States

Sutter Auburn Faith Hospital

🇺🇸

Auburn, California, United States

Sutter Cancer Centers Radiation Oncology Services-Auburn

🇺🇸

Auburn, California, United States

Kaiser Permanente-Baldwin Park

🇺🇸

Baldwin Park, California, United States

Kaiser Permanente-Bellflower

🇺🇸

Bellflower, California, United States

Alta Bates Summit Medical Center-Herrick Campus

🇺🇸

Berkeley, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center

🇺🇸

Burbank, California, United States

Mills-Peninsula Medical Center

🇺🇸

Burlingame, California, United States

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

🇺🇸

Cameron Park, California, United States

Eden Hospital Medical Center

🇺🇸

Castro Valley, California, United States

Enloe Medical Center

🇺🇸

Chico, California, United States

Community Cancer Institute

🇺🇸

Clovis, California, United States

University Oncology Associates

🇺🇸

Clovis, California, United States

Sutter Davis Hospital

🇺🇸

Davis, California, United States

Kaiser Permanente Dublin

🇺🇸

Dublin, California, United States

Kaiser Permanente-Fontana

🇺🇸

Fontana, California, United States

Kaiser Permanente-Fremont

🇺🇸

Fremont, California, United States

Palo Alto Medical Foundation-Fremont

🇺🇸

Fremont, California, United States

Fresno Cancer Center

🇺🇸

Fresno, California, United States

Kaiser Permanente-Fresno

🇺🇸

Fresno, California, United States

Kaiser Permanente South Bay

🇺🇸

Harbor City, California, United States

Kaiser Permanente-Irvine

🇺🇸

Irvine, California, United States

UC San Diego Moores Cancer Center

🇺🇸

La Jolla, California, United States

Kaiser Permanente Los Angeles Medical Center

🇺🇸

Los Angeles, California, United States

Los Angeles General Medical Center

🇺🇸

Los Angeles, California, United States

USC / Norris Comprehensive Cancer Center

🇺🇸

Los Angeles, California, United States

Kaiser Permanente West Los Angeles

🇺🇸

Los Angeles, California, United States

Fremont - Rideout Cancer Center

🇺🇸

Marysville, California, United States

Memorial Medical Center

🇺🇸

Modesto, California, United States

Kaiser Permanente-Modesto

🇺🇸

Modesto, California, United States

Palo Alto Medical Foundation-Camino Division

🇺🇸

Mountain View, California, United States

Palo Alto Medical Foundation-Gynecologic Oncology

🇺🇸

Mountain View, California, United States

USC Norris Oncology/Hematology-Newport Beach

🇺🇸

Newport Beach, California, United States

Sutter Cancer Research Consortium

🇺🇸

Novato, California, United States

Kaiser Permanente Oakland-Broadway

🇺🇸

Oakland, California, United States

Kaiser Permanente-Oakland

🇺🇸

Oakland, California, United States

Kaiser Permanente-Ontario

🇺🇸

Ontario, California, United States

Saint Joseph Hospital - Orange

🇺🇸

Orange, California, United States

Palo Alto Medical Foundation Health Care

🇺🇸

Palo Alto, California, United States

Stanford Cancer Institute Palo Alto

🇺🇸

Palo Alto, California, United States

Kaiser Permanente - Panorama City

🇺🇸

Panorama City, California, United States

Keck Medical Center of USC Pasadena

🇺🇸

Pasadena, California, United States

Kaiser Permanente-Rancho Cordova Cancer Center

🇺🇸

Rancho Cordova, California, United States

Eisenhower Medical Center

🇺🇸

Rancho Mirage, California, United States

Kaiser Permanente-Redwood City

🇺🇸

Redwood City, California, United States

Kaiser Permanente-Richmond

🇺🇸

Richmond, California, United States

Kaiser Permanente-Riverside

🇺🇸

Riverside, California, United States

Rohnert Park Cancer Center

🇺🇸

Rohnert Park, California, United States

Kaiser Permanente-Roseville

🇺🇸

Roseville, California, United States

Sutter Cancer Centers Radiation Oncology Services-Roseville

🇺🇸

Roseville, California, United States

Sutter Roseville Medical Center

🇺🇸

Roseville, California, United States

The Permanente Medical Group-Roseville Radiation Oncology

🇺🇸

Roseville, California, United States

Kaiser Permanente Downtown Commons

🇺🇸

Sacramento, California, United States

Sutter Medical Center Sacramento

🇺🇸

Sacramento, California, United States

University of California Davis Comprehensive Cancer Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente-South Sacramento

🇺🇸

Sacramento, California, United States

South Sacramento Cancer Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente Sacramento Medical Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente-San Diego Mission

🇺🇸

San Diego, California, United States

Kaiser Permanente-San Diego Zion

🇺🇸

San Diego, California, United States

Zuckerberg San Francisco General Hospital

🇺🇸

San Francisco, California, United States

California Pacific Medical Center-Pacific Campus

🇺🇸

San Francisco, California, United States

Kaiser Permanente-San Francisco

🇺🇸

San Francisco, California, United States

Kaiser Permanente-Santa Teresa-San Jose

🇺🇸

San Jose, California, United States

Kaiser Permanente San Leandro

🇺🇸

San Leandro, California, United States

Kaiser Permanente-San Marcos

🇺🇸

San Marcos, California, United States

Mills Health Center

🇺🇸

San Mateo, California, United States

Kaiser Permanente-San Rafael

🇺🇸

San Rafael, California, United States

Kaiser San Rafael-Gallinas

🇺🇸

San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara

🇺🇸

Santa Clara, California, United States

Palo Alto Medical Foundation-Santa Cruz

🇺🇸

Santa Cruz, California, United States

Mission Hope Medical Oncology - Santa Maria

🇺🇸

Santa Maria, California, United States

Kaiser Permanente-Santa Rosa

🇺🇸

Santa Rosa, California, United States

Sutter Pacific Medical Foundation

🇺🇸

Santa Rosa, California, United States

Kaiser Permanente Cancer Treatment Center

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-South San Francisco

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-Stockton

🇺🇸

Stockton, California, United States

Palo Alto Medical Foundation-Sunnyvale

🇺🇸

Sunnyvale, California, United States

Kaiser Permanente Medical Center-Vacaville

🇺🇸

Vacaville, California, United States

Kaiser Permanente-Vallejo

🇺🇸

Vallejo, California, United States

Sutter Solano Medical Center/Cancer Center

🇺🇸

Vallejo, California, United States

Kaiser Permanente-Walnut Creek

🇺🇸

Walnut Creek, California, United States

Kaiser Permanente-Woodland Hills

🇺🇸

Woodland Hills, California, United States

Rocky Mountain Cancer Centers-Aurora

🇺🇸

Aurora, Colorado, United States

The Medical Center of Aurora

🇺🇸

Aurora, Colorado, United States

UCHealth University of Colorado Hospital

🇺🇸

Aurora, Colorado, United States

Rocky Mountain Cancer Centers-Boulder

🇺🇸

Boulder, Colorado, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose

🇺🇸

Colorado Springs, Colorado, United States

UCHealth Memorial Hospital Central

🇺🇸

Colorado Springs, Colorado, United States

Memorial Hospital North

🇺🇸

Colorado Springs, Colorado, United States

Cancer Center of Colorado at Sloan's Lake

🇺🇸

Denver, Colorado, United States

Denver Health Medical Center

🇺🇸

Denver, Colorado, United States

Kaiser Permanente-Franklin

🇺🇸

Denver, Colorado, United States

National Jewish Health-Main Campus

🇺🇸

Denver, Colorado, United States

The Women's Imaging Center

🇺🇸

Denver, Colorado, United States

AdventHealth Porter

🇺🇸

Denver, Colorado, United States

Colorado Blood Cancer Institute

🇺🇸

Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown

🇺🇸

Denver, Colorado, United States

Saint Joseph Hospital - Cancer Centers of Colorado

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose

🇺🇸

Denver, Colorado, United States

Rose Medical Center

🇺🇸

Denver, Colorado, United States

Western Surgical Care

🇺🇸

Denver, Colorado, United States

Mercy Medical Center

🇺🇸

Springfield, Massachusetts, United States

Southwest Oncology PC

🇺🇸

Durango, Colorado, United States

Mountain Blue Cancer Care Center - Swedish

🇺🇸

Englewood, Colorado, United States

Swedish Medical Center

🇺🇸

Englewood, Colorado, United States

Poudre Valley Hospital

🇺🇸

Fort Collins, Colorado, United States

Mountain Blue Cancer Care Center

🇺🇸

Golden, Colorado, United States

National Jewish Health-Western Hematology Oncology

🇺🇸

Golden, Colorado, United States

Saint Mary's Hospital and Regional Medical Center

🇺🇸

Grand Junction, Colorado, United States

Banner North Colorado Medical Center

🇺🇸

Greeley, Colorado, United States

Good Samaritan Hospital - Cancer Centers of Colorado

🇺🇸

Lafayette, Colorado, United States

Kaiser Permanente-Rock Creek

🇺🇸

Lafayette, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood

🇺🇸

Lakewood, Colorado, United States

Saint Anthony Hospital

🇺🇸

Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton

🇺🇸

Littleton, Colorado, United States

AdventHealth Littleton

🇺🇸

Littleton, Colorado, United States

Kaiser Permanente-Lone Tree

🇺🇸

Lone Tree, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge

🇺🇸

Lone Tree, Colorado, United States

Sky Ridge Medical Center

🇺🇸

Lone Tree, Colorado, United States

Longmont United Hospital

🇺🇸

Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont

🇺🇸

Longmont, Colorado, United States

Banner McKee Medical Center

🇺🇸

Loveland, Colorado, United States

AdventHealth Parker

🇺🇸

Parker, Colorado, United States

Rocky Mountain Cancer Centers-Parker

🇺🇸

Parker, Colorado, United States

Saint Mary Corwin Medical Center

🇺🇸

Pueblo, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo

🇺🇸

Pueblo, Colorado, United States

National Jewish Health-Northern Hematology Oncology

🇺🇸

Thornton, Colorado, United States

Rocky Mountain Cancer Centers-Thornton

🇺🇸

Thornton, Colorado, United States

Intermountain Health Lutheran Hospital

🇺🇸

Wheat Ridge, Colorado, United States

Beebe Medical Center

🇺🇸

Lewes, Delaware, United States

Beebe South Coastal Health Campus

🇺🇸

Millville, Delaware, United States

Delaware Clinical and Laboratory Physicians PA

🇺🇸

Newark, Delaware, United States

Helen F Graham Cancer Center

🇺🇸

Newark, Delaware, United States

Medical Oncology Hematology Consultants PA

🇺🇸

Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital

🇺🇸

Newark, Delaware, United States

Beebe Health Campus

🇺🇸

Rehoboth Beach, Delaware, United States

TidalHealth Nanticoke / Allen Cancer Center

🇺🇸

Seaford, Delaware, United States

Christiana Care Health System-Wilmington Hospital

🇺🇸

Wilmington, Delaware, United States

George Washington University Medical Center

🇺🇸

Washington, District of Columbia, United States

AdventHealth Altamonte

🇺🇸

Altamonte Springs, Florida, United States

Mount Sinai Comprehensive Cancer Center at Aventura

🇺🇸

Aventura, Florida, United States

AdventHealth Celebration

🇺🇸

Celebration, Florida, United States

UM Sylvester Comprehensive Cancer Center at Coral Gables

🇺🇸

Coral Gables, Florida, United States

UM Sylvester Comprehensive Cancer Center at Deerfield Beach

🇺🇸

Deerfield Beach, Florida, United States

Holy Cross Hospital

🇺🇸

Fort Lauderdale, Florida, United States

Broward Health Medical Center

🇺🇸

Fort Lauderdale, Florida, United States

University of Florida Health Science Center - Gainesville

🇺🇸

Gainesville, Florida, United States

Memorial Regional Hospital/Joe DiMaggio Children's Hospital

🇺🇸

Hollywood, Florida, United States

Mayo Clinic in Florida

🇺🇸

Jacksonville, Florida, United States

AdventHealth Kissimmee

🇺🇸

Kissimmee, Florida, United States

Mount Sinai Medical Center

🇺🇸

Miami Beach, Florida, United States

University of Miami Miller School of Medicine-Sylvester Cancer Center

🇺🇸

Miami, Florida, United States

UM Sylvester Comprehensive Cancer Center at Kendall

🇺🇸

Miami, Florida, United States

AdventHealth Medical Group Urology at Orlando

🇺🇸

Orlando, Florida, United States

AdventHealth Orlando

🇺🇸

Orlando, Florida, United States

AdventHealth East Orlando

🇺🇸

Orlando, Florida, United States

Memorial Hospital West

🇺🇸

Pembroke Pines, Florida, United States

Sacred Heart Hospital

🇺🇸

Pensacola, Florida, United States

Cleveland Clinic-Weston

🇺🇸

Weston, Florida, United States

AdventHealth Winter Park

🇺🇸

Winter Park, Florida, United States

Grady Health System

🇺🇸

Atlanta, Georgia, United States

Emory University Hospital Midtown

🇺🇸

Atlanta, Georgia, United States

Piedmont Hospital

🇺🇸

Atlanta, Georgia, United States

Emory University Hospital/Winship Cancer Institute

🇺🇸

Atlanta, Georgia, United States

Emory Saint Joseph's Hospital

🇺🇸

Atlanta, Georgia, United States

Atlanta VA Medical Center

🇺🇸

Decatur, Georgia, United States

Piedmont Fayette Hospital

🇺🇸

Fayetteville, Georgia, United States

Emory Johns Creek Hospital

🇺🇸

Johns Creek, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

🇺🇸

Savannah, Georgia, United States

Summit Cancer Care-Candler

🇺🇸

Savannah, Georgia, United States

Kaiser Permanente Moanalua Medical Center

🇺🇸

Honolulu, Hawaii, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

Saint Luke's Cancer Institute - Boise

🇺🇸

Boise, Idaho, United States

Saint Alphonsus Cancer Care Center-Caldwell

🇺🇸

Caldwell, Idaho, United States

Kootenai Health - Coeur d'Alene

🇺🇸

Coeur d'Alene, Idaho, United States

Walter Knox Memorial Hospital

🇺🇸

Emmett, Idaho, United States

Saint Luke's Cancer Institute - Fruitland

🇺🇸

Fruitland, Idaho, United States

Idaho Urologic Institute-Meridian

🇺🇸

Meridian, Idaho, United States

Saint Luke's Cancer Institute - Meridian

🇺🇸

Meridian, Idaho, United States

Saint Alphonsus Cancer Care Center-Nampa

🇺🇸

Nampa, Idaho, United States

Saint Luke's Cancer Institute - Nampa

🇺🇸

Nampa, Idaho, United States

Kootenai Clinic Cancer Services - Post Falls

🇺🇸

Post Falls, Idaho, United States

Kootenai Clinic Cancer Services - Sandpoint

🇺🇸

Sandpoint, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls

🇺🇸

Twin Falls, Idaho, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

Loyola Center for Health at Burr Ridge

🇺🇸

Burr Ridge, Illinois, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Memorial Hospital of Carbondale

🇺🇸

Carbondale, Illinois, United States

SIH Cancer Institute

🇺🇸

Carterville, Illinois, United States

Illinois CancerCare-Carthage

🇺🇸

Carthage, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Northwestern University

🇺🇸

Chicago, Illinois, United States

Rush University Medical Center

🇺🇸

Chicago, Illinois, United States

University of Illinois

🇺🇸

Chicago, Illinois, United States

Carle at The Riverfront

🇺🇸

Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Illinois CancerCare-Dixon

🇺🇸

Dixon, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

NorthShore University HealthSystem-Evanston Hospital

🇺🇸

Evanston, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center

🇺🇸

Galesburg, Illinois, United States

NorthShore University HealthSystem-Glenbrook Hospital

🇺🇸

Glenview, Illinois, United States

NorthShore University HealthSystem-Highland Park Hospital

🇺🇸

Highland Park, Illinois, United States

Loyola Medicine Homer Glen

🇺🇸

Homer Glen, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Northwestern Medicine Lake Forest Hospital

🇺🇸

Lake Forest, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

Loyola University Medical Center

🇺🇸

Maywood, Illinois, United States

Marjorie Weinberg Cancer Center at Loyola-Gottlieb

🇺🇸

Melrose Park, Illinois, United States

SSM Health Good Samaritan

🇺🇸

Mount Vernon, Illinois, United States

Cancer Care Center of O'Fallon

🇺🇸

O'Fallon, Illinois, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

OSF Saint Francis Radiation Oncology at Pekin

🇺🇸

Pekin, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

🇺🇸

Peoria, Illinois, United States

Methodist Medical Center of Illinois

🇺🇸

Peoria, Illinois, United States

OSF Saint Francis Medical Center

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Valley Radiation Oncology

🇺🇸

Peru, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

Springfield Clinic

🇺🇸

Springfield, Illinois, United States

Springfield Memorial Hospital

🇺🇸

Springfield, Illinois, United States

Southwest Illinois Health Services LLP

🇺🇸

Swansea, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Illinois CancerCare - Washington

🇺🇸

Washington, Illinois, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

IU Health North Hospital

🇺🇸

Carmel, Indiana, United States

Indiana University/Melvin and Bren Simon Cancer Center

🇺🇸

Indianapolis, Indiana, United States

Sidney and Lois Eskenazi Hospital

🇺🇸

Indianapolis, Indiana, United States

Franciscan Health Indianapolis

🇺🇸

Indianapolis, Indiana, United States

Springmill Medical Center

🇺🇸

Indianapolis, Indiana, United States

Franciscan Saint Elizabeth Health - Lafayette East

🇺🇸

Lafayette, Indiana, United States

Woodland Cancer Care Center

🇺🇸

Michigan City, Indiana, United States

Franciscan Health Mooresville

🇺🇸

Mooresville, Indiana, United States

Baptist Health Floyd

🇺🇸

New Albany, Indiana, United States

Union Hospital

🇺🇸

Terre Haute, Indiana, United States

University of Iowa Healthcare Cancer Services Quad Cities

🇺🇸

Bettendorf, Iowa, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

🇺🇸

Clive, Iowa, United States

Alegent Health Mercy Hospital

🇺🇸

Council Bluffs, Iowa, United States

Greater Regional Medical Center

🇺🇸

Creston, Iowa, United States

Iowa Methodist Medical Center

🇺🇸

Des Moines, Iowa, United States

UI Health Care Mission Cancer and Blood - Des Moines Clinic

🇺🇸

Des Moines, Iowa, United States

Broadlawns Medical Center

🇺🇸

Des Moines, Iowa, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

UI Health Care Mission Cancer and Blood - Laurel Clinic

🇺🇸

Des Moines, Iowa, United States

Iowa Lutheran Hospital

🇺🇸

Des Moines, Iowa, United States

Trinity Regional Medical Center

🇺🇸

Fort Dodge, Iowa, United States

University of Iowa/Holden Comprehensive Cancer Center

🇺🇸

Iowa City, Iowa, United States

Methodist West Hospital

🇺🇸

West Des Moines, Iowa, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Cancer Center of Kansas - Chanute

🇺🇸

Chanute, Kansas, United States

Cancer Center of Kansas - Dodge City

🇺🇸

Dodge City, Kansas, United States

Cancer Center of Kansas - El Dorado

🇺🇸

El Dorado, Kansas, United States

University of Kansas Clinical Research Center

🇺🇸

Fairway, Kansas, United States

Cancer Center of Kansas-Independence

🇺🇸

Independence, Kansas, United States

Cancer Center of Kansas-Kingman

🇺🇸

Kingman, Kansas, United States

Lawrence Memorial Hospital

🇺🇸

Lawrence, Kansas, United States

Cancer Center of Kansas-Liberal

🇺🇸

Liberal, Kansas, United States

Cancer Center of Kansas-Manhattan

🇺🇸

Manhattan, Kansas, United States

Cancer Center of Kansas - McPherson

🇺🇸

McPherson, Kansas, United States

Cancer Center of Kansas - Newton

🇺🇸

Newton, Kansas, United States

The University of Kansas Cancer Center - Olathe

🇺🇸

Olathe, Kansas, United States

Cancer Center of Kansas - Parsons

🇺🇸

Parsons, Kansas, United States

Mercy Hospital Pittsburg

🇺🇸

Pittsburg, Kansas, United States

Cancer Center of Kansas - Pratt

🇺🇸

Pratt, Kansas, United States

Cancer Center of Kansas - Salina

🇺🇸

Salina, Kansas, United States

Salina Regional Health Center

🇺🇸

Salina, Kansas, United States

University of Kansas Health System Saint Francis Campus

🇺🇸

Topeka, Kansas, United States

Cancer Center of Kansas - Wellington

🇺🇸

Wellington, Kansas, United States

University of Kansas Hospital-Westwood Cancer Center

🇺🇸

Westwood, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower

🇺🇸

Wichita, Kansas, United States

Ascension Via Christi Hospitals Wichita

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Wichita

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Winfield

🇺🇸

Winfield, Kansas, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Baptist Health Corbin

🇺🇸

Corbin, Kentucky, United States

Commonwealth Cancer Center-Corbin

🇺🇸

Corbin, Kentucky, United States

Baptist Health Lexington

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

Saint Joseph London

🇺🇸

London, Kentucky, United States

Jewish Hospital

🇺🇸

Louisville, Kentucky, United States

The James Graham Brown Cancer Center at University of Louisville

🇺🇸

Louisville, Kentucky, United States

Baptist Health Louisville

🇺🇸

Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Baptist Health Madisonville/Merle Mahr Cancer Center

🇺🇸

Madisonville, Kentucky, United States

Baptist Health Paducah

🇺🇸

Paducah, Kentucky, United States

Jewish Hospital Medical Center South

🇺🇸

Shepherdsville, Kentucky, United States

LSU Health Baton Rouge-North Clinic

🇺🇸

Baton Rouge, Louisiana, United States

Our Lady of the Lake Physician Group

🇺🇸

Baton Rouge, Louisiana, United States

Louisiana Hematology Oncology Associates LLC

🇺🇸

Baton Rouge, Louisiana, United States

Mary Bird Perkins Cancer Center

🇺🇸

Baton Rouge, Louisiana, United States

East Jefferson General Hospital

🇺🇸

Metairie, Louisiana, United States

Louisiana State University Health Science Center

🇺🇸

New Orleans, Louisiana, United States

Greater Baltimore Medical Center

🇺🇸

Baltimore, Maryland, United States

Boston Medical Center

🇺🇸

Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center

🇺🇸

Boston, Massachusetts, United States

Dana-Farber Cancer Institute

🇺🇸

Boston, Massachusetts, United States

Simonds-Sinon Regional Cancer Center

🇺🇸

Fitchburg, Massachusetts, United States

UMass Memorial Medical Center - University Campus

🇺🇸

Worcester, Massachusetts, United States

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

🇺🇸

Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center

🇺🇸

Ann Arbor, Michigan, United States

Bronson Battle Creek

🇺🇸

Battle Creek, Michigan, United States

McLaren Cancer Institute-Bay City

🇺🇸

Bay City, Michigan, United States

McLaren Cancer Institute-Bloomfield

🇺🇸

Bloomfield, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton

🇺🇸

Brighton, Michigan, United States

Trinity Health Medical Center - Brighton

🇺🇸

Brighton, Michigan, United States

University of Michigan - Brighton Center for Specialty Care

🇺🇸

Brighton, Michigan, United States

Henry Ford Cancer Institute-Downriver

🇺🇸

Brownstown, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Canton

🇺🇸

Canton, Michigan, United States

Trinity Health Medical Center - Canton

🇺🇸

Canton, Michigan, United States

Caro Cancer Center

🇺🇸

Caro, Michigan, United States

Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston

🇺🇸

Clarkston, Michigan, United States

McLaren Cancer Institute-Clarkston

🇺🇸

Clarkston, Michigan, United States

Newland Medical Associates-Clarkston

🇺🇸

Clarkston, Michigan, United States

Henry Ford Macomb Hospital-Clinton Township

🇺🇸

Clinton Township, Michigan, United States

Corewell Health Dearborn Hospital

🇺🇸

Dearborn, Michigan, United States

Henry Ford Medical Center-Fairlane

🇺🇸

Dearborn, Michigan, United States

Wayne State University/Karmanos Cancer Institute

🇺🇸

Detroit, Michigan, United States

Henry Ford Hospital

🇺🇸

Detroit, Michigan, United States

Henry Ford Health Saint John Hospital

🇺🇸

Detroit, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital

🇺🇸

Livonia, Michigan, United States

Henry Ford River District Hospital

🇺🇸

East China Township, Michigan, United States

Weisberg Cancer Treatment Center

🇺🇸

Farmington Hills, Michigan, United States

Corewell Health Farmington Hills Hospital

🇺🇸

Farmington Hills, Michigan, United States

Cancer Hematology Centers - Flint

🇺🇸

Flint, Michigan, United States

Genesee Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

McLaren Cancer Institute-Flint

🇺🇸

Flint, Michigan, United States

Singh and Arora Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

🇺🇸

Grand Rapids, Michigan, United States

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital

🇺🇸

Grand Rapids, Michigan, United States

Trinity Health Grand Rapids Hospital

🇺🇸

Grand Rapids, Michigan, United States

Henry Ford Saint John Hospital - Academic

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Breast

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Van Elslander

🇺🇸

Grosse Pointe Woods, Michigan, United States

William Beaumont Hospital-Grosse Pointe

🇺🇸

Grosse Pointe, Michigan, United States

Allegiance Health

🇺🇸

Jackson, Michigan, United States

Bronson Methodist Hospital

🇺🇸

Kalamazoo, Michigan, United States

West Michigan Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Ascension Borgess Hospital

🇺🇸

Kalamazoo, Michigan, United States

Karmanos Cancer Institute at McLaren Greater Lansing

🇺🇸

Lansing, Michigan, United States

Mid-Michigan Physicians-Lansing

🇺🇸

Lansing, Michigan, United States

University of Michigan Health - Sparrow Lansing

🇺🇸

Lansing, Michigan, United States

McLaren Cancer Institute-Lapeer Region

🇺🇸

Lapeer, Michigan, United States

Hope Cancer Clinic

🇺🇸

Livonia, Michigan, United States

Henry Ford Saint John Hospital - Macomb Medical

🇺🇸

Macomb, Michigan, United States

Henry Ford Warren Hospital - Breast Macomb

🇺🇸

Macomb, Michigan, United States

Saint Mary's Oncology/Hematology Associates of Marlette

🇺🇸

Marlette, Michigan, United States

McLaren Cancer Institute-Macomb

🇺🇸

Mount Clemens, Michigan, United States

McLaren Cancer Institute-Central Michigan

🇺🇸

Mount Pleasant, Michigan, United States

Trinity Health Muskegon Hospital

🇺🇸

Muskegon, Michigan, United States

Corewell Health Lakeland Hospitals - Niles Hospital

🇺🇸

Niles, Michigan, United States

Cancer and Hematology Centers of Western Michigan - Norton Shores

🇺🇸

Norton Shores, Michigan, United States

Henry Ford Health Providence Novi Hospital

🇺🇸

Novi, Michigan, United States

Henry Ford Medical Center-Columbus

🇺🇸

Novi, Michigan, United States

McLaren Cancer Institute-Northern Michigan

🇺🇸

Petoskey, Michigan, United States

Hope Cancer Center

🇺🇸

Pontiac, Michigan, United States

Michigan Healthcare Professionals Pontiac

🇺🇸

Pontiac, Michigan, United States

Newland Medical Associates-Pontiac

🇺🇸

Pontiac, Michigan, United States

Trinity Health Saint Joseph Mercy Oakland Hospital

🇺🇸

Pontiac, Michigan, United States

McLaren-Port Huron

🇺🇸

Port Huron, Michigan, United States

Corewell Health Reed City Hospital

🇺🇸

Reed City, Michigan, United States

Henry Ford Rochester Hospital

🇺🇸

Rochester Hills, Michigan, United States

Michigan Cancer Specialists

🇺🇸

Roseville, Michigan, United States

Oakland Colon Rectal Associates

🇺🇸

Royal Oak, Michigan, United States

Cancer Care Associates PC

🇺🇸

Royal Oak, Michigan, United States

Comprehensive Medical Center PLLC

🇺🇸

Royal Oak, Michigan, United States

Corewell Health William Beaumont University Hospital

🇺🇸

Royal Oak, Michigan, United States

Hematology Oncology Consultants PC-Royal Oak

🇺🇸

Royal Oak, Michigan, United States

Oakland Medical Group

🇺🇸

Royal Oak, Michigan, United States

MyMichigan Medical Center Saginaw

🇺🇸

Saginaw, Michigan, United States

Covenant HealthCare Mackinaw

🇺🇸

Saginaw, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC

🇺🇸

Saginaw, Michigan, United States

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

🇺🇸

Saint Joseph, Michigan, United States

Corewell Health Lakeland Hospitals - Saint Joseph Hospital

🇺🇸

Saint Joseph, Michigan, United States

Henry Ford Macomb Health Center - Shelby Township

🇺🇸

Shelby, Michigan, United States

Henry Ford Health Providence Southfield Hospital

🇺🇸

Southfield, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights

🇺🇸

Sterling Heights, Michigan, United States

Premier Hematology Oncology Care

🇺🇸

Sterling Heights, Michigan, United States

Mitchell Folbe MD PC

🇺🇸

Sterling Heights, Michigan, United States

MyMichigan Medical Center Tawas

🇺🇸

Tawas City, Michigan, United States

Munson Medical Center

🇺🇸

Traverse City, Michigan, United States

Michigan Institute of Urology-Town Center

🇺🇸

Troy, Michigan, United States

Claudia BR Herke MD PC

🇺🇸

Troy, Michigan, United States

Corewell Health Beaumont Troy Hospital

🇺🇸

Troy, Michigan, United States

Hematology Oncology Consultants PC-Troy

🇺🇸

Troy, Michigan, United States

Advanced Breast Care Center PLLC

🇺🇸

Warren, Michigan, United States

Henry Ford Health Warren Hospital

🇺🇸

Warren, Michigan, United States

Henry Ford Madison Heights Hospital - Breast

🇺🇸

Warren, Michigan, United States

Henry Ford Warren Hospital - GLCMS

🇺🇸

Warren, Michigan, United States

Macomb Hematology Oncology PC

🇺🇸

Warren, Michigan, United States

Henry Ford West Bloomfield Hospital

🇺🇸

West Bloomfield, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch

🇺🇸

West Branch, Michigan, United States

University of Michigan Health - West

🇺🇸

Wyoming, Michigan, United States

Huron Gastroenterology PC

🇺🇸

Ypsilanti, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

🇺🇸

Ypsilanti, Michigan, United States

Riverwood Healthcare Center

🇺🇸

Aitkin, Minnesota, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Essentia Health Saint Joseph's Medical Center

🇺🇸

Brainerd, Minnesota, United States

Fairview Ridges Hospital

🇺🇸

Burnsville, Minnesota, United States

Minnesota Oncology - Burnsville

🇺🇸

Burnsville, Minnesota, United States

Cambridge Medical Center

🇺🇸

Cambridge, Minnesota, United States

Mercy Hospital

🇺🇸

Coon Rapids, Minnesota, United States

Essentia Health - Deer River Clinic

🇺🇸

Deer River, Minnesota, United States

Essentia Health Saint Mary's - Detroit Lakes Clinic

🇺🇸

Detroit Lakes, Minnesota, United States

Essentia Health Cancer Center

🇺🇸

Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center

🇺🇸

Duluth, Minnesota, United States

Miller-Dwan Hospital

🇺🇸

Duluth, Minnesota, United States

Fairview Southdale Hospital

🇺🇸

Edina, Minnesota, United States

Lake Region Healthcare Corporation-Cancer Care

🇺🇸

Fergus Falls, Minnesota, United States

Essentia Health - Fosston

🇺🇸

Fosston, Minnesota, United States

Unity Hospital

🇺🇸

Fridley, Minnesota, United States

Essentia Health Hibbing Clinic

🇺🇸

Hibbing, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove

🇺🇸

Maple Grove, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood

🇺🇸

Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast

🇺🇸

Maplewood, Minnesota, United States

Abbott-Northwestern Hospital

🇺🇸

Minneapolis, Minnesota, United States

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Health Partners Inc

🇺🇸

Minneapolis, Minnesota, United States

Monticello Cancer Center

🇺🇸

Monticello, Minnesota, United States

New Ulm Medical Center

🇺🇸

New Ulm, Minnesota, United States

Essentia Health - Park Rapids

🇺🇸

Park Rapids, Minnesota, United States

Fairview Northland Medical Center

🇺🇸

Princeton, Minnesota, United States

North Memorial Medical Health Center

🇺🇸

Robbinsdale, Minnesota, United States

Mayo Clinic in Rochester

🇺🇸

Rochester, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park

🇺🇸

Saint Louis Park, Minnesota, United States

Regions Hospital

🇺🇸

Saint Paul, Minnesota, United States

United Hospital

🇺🇸

Saint Paul, Minnesota, United States

Essentia Health Sandstone

🇺🇸

Sandstone, Minnesota, United States

Saint Francis Regional Medical Center

🇺🇸

Shakopee, Minnesota, United States

Lakeview Hospital

🇺🇸

Stillwater, Minnesota, United States

Sanford Thief River Falls Medical Center

🇺🇸

Thief River Falls, Minnesota, United States

Essentia Health Virginia Clinic

🇺🇸

Virginia, Minnesota, United States

Ridgeview Medical Center

🇺🇸

Waconia, Minnesota, United States

Rice Memorial Hospital

🇺🇸

Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury

🇺🇸

Woodbury, Minnesota, United States

Sanford Cancer Center Worthington

🇺🇸

Worthington, Minnesota, United States

Fairview Lakes Medical Center

🇺🇸

Wyoming, Minnesota, United States

Baptist Cancer Center-Grenada

🇺🇸

Grenada, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Union County

🇺🇸

New Albany, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Oxford

🇺🇸

Oxford, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Desoto

🇺🇸

Southhaven, Mississippi, United States

Saint Louis Cancer and Breast Institute-Ballwin

🇺🇸

Ballwin, Missouri, United States

Parkland Health Center-Bonne Terre

🇺🇸

Bonne Terre, Missouri, United States

Cox Cancer Center Branson

🇺🇸

Branson, Missouri, United States

Mercy Cancer Center - Cape Girardeau

🇺🇸

Cape Girardeau, Missouri, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

Saint Luke's Hospital

🇺🇸

Chesterfield, Missouri, United States

Siteman Cancer Center at West County Hospital

🇺🇸

Creve Coeur, Missouri, United States

Parkland Health Center - Farmington

🇺🇸

Farmington, Missouri, United States

MU Health Care Goldschmidt Cancer Center

🇺🇸

Jefferson City, Missouri, United States

Freeman Health System

🇺🇸

Joplin, Missouri, United States

Mercy Hospital Joplin

🇺🇸

Joplin, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology

🇺🇸

Rolla, Missouri, United States

Phelps Health Delbert Day Cancer Institute

🇺🇸

Rolla, Missouri, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City

🇺🇸

Saint Louis, Missouri, United States

Washington University School of Medicine

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital South

🇺🇸

Saint Louis, Missouri, United States

Siteman Cancer Center-South County

🇺🇸

Saint Louis, Missouri, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Saint Louis

🇺🇸

Saint Louis, Missouri, United States

Siteman Cancer Center at Saint Peters Hospital

🇺🇸

Saint Peters, Missouri, United States

Sainte Genevieve County Memorial Hospital

🇺🇸

Sainte Genevieve, Missouri, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital

🇺🇸

Sullivan, Missouri, United States

BJC Outpatient Center at Sunset Hills

🇺🇸

Sunset Hills, Missouri, United States

Mercy Hospital Washington

🇺🇸

Washington, Missouri, United States

Community Hospital of Anaconda

🇺🇸

Anaconda, Montana, United States

Billings Clinic Cancer Center

🇺🇸

Billings, Montana, United States

Saint Vincent Healthcare

🇺🇸

Billings, Montana, United States

Saint Vincent Frontier Cancer Center

🇺🇸

Billings, Montana, United States

Bozeman Health Deaconess Hospital

🇺🇸

Bozeman, Montana, United States

Saint James Community Hospital and Cancer Treatment Center

🇺🇸

Butte, Montana, United States

Benefis Sletten Cancer Institute

🇺🇸

Great Falls, Montana, United States

Great Falls Clinic

🇺🇸

Great Falls, Montana, United States

Saint Peter's Community Hospital

🇺🇸

Helena, Montana, United States

Logan Health Medical Center

🇺🇸

Kalispell, Montana, United States

Saint Patrick Hospital - Community Hospital

🇺🇸

Missoula, Montana, United States

Community Medical Center

🇺🇸

Missoula, Montana, United States

Nebraska Cancer Specialists/Oncology Hematology West PC

🇺🇸

Grand Island, Nebraska, United States

Fred and Pamela Buffett Cancer Center - Kearney

🇺🇸

Kearney, Nebraska, United States

CHI Health Good Samaritan

🇺🇸

Kearney, Nebraska, United States

Saint Elizabeth Regional Medical Center

🇺🇸

Lincoln, Nebraska, United States

Nebraska Methodist Hospital

🇺🇸

Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Hematology and Oncology Consultants PC

🇺🇸

Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

Midlands Community Hospital

🇺🇸

Papillion, Nebraska, United States

Carson Tahoe Regional Medical Center

🇺🇸

Carson City, Nevada, United States

Cancer and Blood Specialists-Henderson

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Henderson

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Horizon Ridge

🇺🇸

Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson

🇺🇸

Henderson, Nevada, United States

OptumCare Cancer Care at Seven Hills

🇺🇸

Henderson, Nevada, United States

Dublin Methodist Hospital

🇺🇸

Dublin, Ohio, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson

🇺🇸

Henderson, Nevada, United States

GenesisCare USA - Henderson

🇺🇸

Henderson, Nevada, United States

Las Vegas Urology - Green Valley

🇺🇸

Henderson, Nevada, United States

Las Vegas Urology - Pebble

🇺🇸

Henderson, Nevada, United States

Urology Specialists of Nevada - Green Valley

🇺🇸

Henderson, Nevada, United States

Las Vegas Urology - Pecos

🇺🇸

Las Vegas, Nevada, United States

Desert West Surgery

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at Charleston

🇺🇸

Las Vegas, Nevada, United States

University Medical Center of Southern Nevada

🇺🇸

Las Vegas, Nevada, United States

Hope Cancer Care of Nevada

🇺🇸

Las Vegas, Nevada, United States

Cancer and Blood Specialists-Shadow

🇺🇸

Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Central

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Central

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Las Vegas

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

🇺🇸

Las Vegas, Nevada, United States

Sunrise Hospital and Medical Center

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Prostate Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Sunset

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Southwest

🇺🇸

Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast

🇺🇸

Las Vegas, Nevada, United States

Ann M Wierman MD LTD

🇺🇸

Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Vegas Tenaya

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Cathedral Rock

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Smoke Ranch

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at MountainView

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

Alliance for Childhood Diseases/Cure 4 the Kids Foundation

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Town Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin

🇺🇸

Las Vegas, Nevada, United States

Summerlin Hospital Medical Center

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Fort Apache

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley

🇺🇸

Las Vegas, Nevada, United States

University Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Hope Cancer Care of Nevada-Pahrump

🇺🇸

Pahrump, Nevada, United States

Renown Regional Medical Center

🇺🇸

Reno, Nevada, United States

Saint Mary's Regional Medical Center

🇺🇸

Reno, Nevada, United States

Radiation Oncology Associates

🇺🇸

Reno, Nevada, United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

🇺🇸

Lebanon, New Hampshire, United States

Memorial Sloan Kettering Basking Ridge

🇺🇸

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth

🇺🇸

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen

🇺🇸

Montvale, New Jersey, United States

Virtua Samson Cancer Center

🇺🇸

Moorestown, New Jersey, United States

Morristown Medical Center

🇺🇸

Morristown, New Jersey, United States

Virtua Memorial

🇺🇸

Mount Holly, New Jersey, United States

Rutgers Cancer Institute of New Jersey

🇺🇸

New Brunswick, New Jersey, United States

Overlook Hospital

🇺🇸

Summit, New Jersey, United States

Holy Name Hospital

🇺🇸

Teaneck, New Jersey, United States

Virtua Voorhees

🇺🇸

Voorhees, New Jersey, United States

Lovelace Medical Center-Saint Joseph Square

🇺🇸

Albuquerque, New Mexico, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

Lovelace Radiation Oncology

🇺🇸

Albuquerque, New Mexico, United States

Presbyterian Kaseman Hospital

🇺🇸

Albuquerque, New Mexico, United States

Presbyterian Rust Medical Center/Jorgensen Cancer Center

🇺🇸

Rio Rancho, New Mexico, United States

Montefiore Medical Center-Einstein Campus

🇺🇸

Bronx, New York, United States

Montefiore Medical Center-Weiler Hospital

🇺🇸

Bronx, New York, United States

Montefiore Medical Center - Moses Campus

🇺🇸

Bronx, New York, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Memorial Sloan Kettering Commack

🇺🇸

Commack, New York, United States

Glens Falls Hospital

🇺🇸

Glens Falls, New York, United States

Memorial Sloan Kettering Westchester

🇺🇸

Harrison, New York, United States

Mount Sinai West

🇺🇸

New York, New York, United States

Mount Sinai Hospital

🇺🇸

New York, New York, United States

Manhattan Eye Ear and Throat Hospital

🇺🇸

New York, New York, United States

Memorial Sloan Kettering Cancer Center

🇺🇸

New York, New York, United States

Lenox Hill Hospital

🇺🇸

New York, New York, United States

Memorial Sloan Kettering Nassau

🇺🇸

Uniondale, New York, United States

Atrium Health Stanly/LCI-Albemarle

🇺🇸

Albemarle, North Carolina, United States

UNC Lineberger Comprehensive Cancer Center

🇺🇸

Chapel Hill, North Carolina, United States

Carolinas Medical Center/Levine Cancer Institute

🇺🇸

Charlotte, North Carolina, United States

Atrium Health Pineville/LCI-Pineville

🇺🇸

Charlotte, North Carolina, United States

Levine Cancer Institute-SouthPark

🇺🇸

Charlotte, North Carolina, United States

Atrium Health University City/LCI-University

🇺🇸

Charlotte, North Carolina, United States

Levine Cancer Institute-Ballantyne

🇺🇸

Charlotte, North Carolina, United States

Wake Forest University at Clemmons

🇺🇸

Clemmons, North Carolina, United States

Southeastern Medical Oncology Center-Clinton

🇺🇸

Clinton, North Carolina, United States

Atrium Health Cabarrus/LCI-Concord

🇺🇸

Concord, North Carolina, United States

Wake Forest University at Elkin

🇺🇸

Elkin, North Carolina, United States

Levine Cancer Institute-Gaston

🇺🇸

Gastonia, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro

🇺🇸

Goldsboro, North Carolina, United States

Wayne Memorial Hospital

🇺🇸

Goldsboro, North Carolina, United States

Margaret R Pardee Memorial Hospital

🇺🇸

Hendersonville, North Carolina, United States

Onslow Memorial Hospital

🇺🇸

Jacksonville, North Carolina, United States

Southeastern Medical Oncology Center-Jacksonville

🇺🇸

Jacksonville, North Carolina, United States

ECU Health Oncology Kenansville

🇺🇸

Kenansville, North Carolina, United States

ECU Health Oncology Kinston

🇺🇸

Kinston, North Carolina, United States

Wake Forest University at Lexington

🇺🇸

Lexington, North Carolina, United States

Atrium Health Lincoln/LCI-Lincolnton

🇺🇸

Lincolnton, North Carolina, United States

Atrium Health Union/LCI-Union

🇺🇸

Monroe, North Carolina, United States

Wake Forest University at Mount Airy

🇺🇸

Mount Airy, North Carolina, United States

Rex Hematology Oncology Associates-Blue Ridge

🇺🇸

Raleigh, North Carolina, United States

UNC Rex Healthcare

🇺🇸

Raleigh, North Carolina, United States

UNC Rex Cancer Center of Wakefield

🇺🇸

Raleigh, North Carolina, United States

ECU Health Oncology Richlands

🇺🇸

Richlands, North Carolina, United States

Wake Forest University Health Sciences

🇺🇸

Winston-Salem, North Carolina, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

Essentia Health Cancer Center-South University Clinic

🇺🇸

Fargo, North Dakota, United States

Sanford South University Medical Center

🇺🇸

Fargo, North Dakota, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

Essentia Health - Jamestown Clinic

🇺🇸

Jamestown, North Dakota, United States

Trinity Cancer Care Center

🇺🇸

Minot, North Dakota, United States

UHHS-Chagrin Highlands Medical Center

🇺🇸

Beachwood, Ohio, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Geauga Hospital

🇺🇸

Chardon, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati

🇺🇸

Cincinnati, Ohio, United States

Bethesda North Hospital

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson

🇺🇸

Cincinnati, Ohio, United States

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

MetroHealth Medical Center

🇺🇸

Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Delaware Radiation Oncology

🇺🇸

Delaware, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Mercy Cancer Center-Elyria

🇺🇸

Elyria, Ohio, United States

Mount Carmel Grove City Hospital

🇺🇸

Grove City, Ohio, United States

Fairfield Medical Center

🇺🇸

Lancaster, Ohio, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

UH Seidman Cancer Center at Landerbrook Health Center

🇺🇸

Mayfield Heights, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus

🇺🇸

Mentor, Ohio, United States

UH Seidman Cancer Center at Southwest General Hospital

🇺🇸

Middleburg Heights, Ohio, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

Newark Radiation Oncology

🇺🇸

Newark, Ohio, United States

University Hospitals Parma Medical Center

🇺🇸

Parma, Ohio, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

University Hospitals Portage Medical Center

🇺🇸

Ravenna, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center

🇺🇸

Sandusky, Ohio, United States

University Hospitals Sharon Health Center

🇺🇸

Wadsworth, Ohio, United States

University of Cincinnati Cancer Center-West Chester

🇺🇸

West Chester, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

UH Seidman Cancer Center at Saint John Medical Center

🇺🇸

Westlake, Ohio, United States

UHHS-Westlake Medical Center

🇺🇸

Westlake, Ohio, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

Cancer Centers of Southwest Oklahoma Research

🇺🇸

Lawton, Oklahoma, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

Oklahoma Cancer Specialists and Research Institute-Tulsa

🇺🇸

Tulsa, Oklahoma, United States

Saint Alphonsus Cancer Care Center-Baker City

🇺🇸

Baker City, Oregon, United States

Saint Charles Health System

🇺🇸

Bend, Oregon, United States

Clackamas Radiation Oncology Center

🇺🇸

Clackamas, Oregon, United States

Providence Cancer Institute Clackamas Clinic

🇺🇸

Clackamas, Oregon, United States

Bay Area Hospital

🇺🇸

Coos Bay, Oregon, United States

Providence Newberg Medical Center

🇺🇸

Newberg, Oregon, United States

Saint Alphonsus Cancer Care Center-Ontario

🇺🇸

Ontario, Oregon, United States

Providence Portland Medical Center

🇺🇸

Portland, Oregon, United States

Providence Saint Vincent Medical Center

🇺🇸

Portland, Oregon, United States

Kaiser Permanente Northwest

🇺🇸

Portland, Oregon, United States

Oregon Health and Science University

🇺🇸

Portland, Oregon, United States

Saint Charles Health System-Redmond

🇺🇸

Redmond, Oregon, United States

Jefferson Abington Hospital

🇺🇸

Abington, Pennsylvania, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

UPMC-Heritage Valley Health System Beaver

🇺🇸

Beaver, Pennsylvania, United States

Saint Luke's University Hospital-Bethlehem Campus

🇺🇸

Bethlehem, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg

🇺🇸

Bethlehem, Pennsylvania, United States

Bryn Mawr Hospital

🇺🇸

Bryn Mawr, Pennsylvania, United States

Christiana Care Health System-Concord Health Center

🇺🇸

Chadds Ford, Pennsylvania, United States

Main Line Health Center-Collegeville

🇺🇸

Collegeville, Pennsylvania, United States

Geisinger Medical Center

🇺🇸

Danville, Pennsylvania, United States

Pocono Medical Center

🇺🇸

East Stroudsburg, Pennsylvania, United States

Main Line Health Center-Exton

🇺🇸

Exton, Pennsylvania, United States

UPMC Cancer Centers - Arnold Palmer Pavilion

🇺🇸

Greensburg, Pennsylvania, United States

UPMC Pinnacle Harrisburg

🇺🇸

Harrisburg, Pennsylvania, United States

UPMC Pinnacle Cancer Center/Community Osteopathic Campus

🇺🇸

Harrisburg, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Lehigh Valley Hospital-Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

UPMC-Johnstown/John P. Murtha Regional Cancer Center

🇺🇸

Johnstown, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg

🇺🇸

Lewisburg, Pennsylvania, United States

Lewistown Hospital

🇺🇸

Lewistown, Pennsylvania, United States

UPMC Cancer Center at UPMC McKeesport

🇺🇸

McKeesport, Pennsylvania, United States

Riddle Memorial Hospital

🇺🇸

Media, Pennsylvania, United States

UPMC Hillman Cancer Center in Coraopolis

🇺🇸

Moon, Pennsylvania, United States

Paoli Memorial Hospital

🇺🇸

Paoli, Pennsylvania, United States

University of Pennsylvania/Abramson Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Pennsylvania Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

Thomas Jefferson University Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Jefferson Torresdale Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

Temple University Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

UPMC-Magee Womens Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

UPMC-Saint Margaret

🇺🇸

Pittsburgh, Pennsylvania, United States

University of Pittsburgh Cancer Institute (UPCI)

🇺🇸

Pittsburgh, Pennsylvania, United States

UPMC-Shadyside Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

UPMC-Passavant Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

UPMC-Saint Clair Hospital Cancer Center

🇺🇸

Pittsburgh, Pennsylvania, United States

Geisinger Cancer Services-Pottsville

🇺🇸

Pottsville, Pennsylvania, United States

UPMC Cancer Center at UPMC Northwest

🇺🇸

Seneca, Pennsylvania, United States

Geisinger Medical Group

🇺🇸

State College, Pennsylvania, United States

UPMC Uniontown Hospital Radiation Oncology

🇺🇸

Uniontown, Pennsylvania, United States

UPMC Washington Hospital Radiation Oncology

🇺🇸

Washington, Pennsylvania, United States

Reading Hospital

🇺🇸

West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

Asplundh Cancer Pavilion

🇺🇸

Willow Grove, Pennsylvania, United States

Lankenau Medical Center

🇺🇸

Wynnewood, Pennsylvania, United States

UPMC Memorial

🇺🇸

York, Pennsylvania, United States

Prisma Health Cancer Institute - Spartanburg

🇺🇸

Boiling Springs, South Carolina, United States

Prisma Health Cancer Institute - Laurens

🇺🇸

Clinton, South Carolina, United States

Prisma Health Cancer Institute - Easley

🇺🇸

Easley, South Carolina, United States

Gibbs Cancer Center-Gaffney

🇺🇸

Gaffney, South Carolina, United States

Tidelands Georgetown Memorial Hospital

🇺🇸

Georgetown, South Carolina, United States

Prisma Health Cancer Institute - Butternut

🇺🇸

Greenville, South Carolina, United States

Prisma Health Cancer Institute - Faris

🇺🇸

Greenville, South Carolina, United States

Prisma Health Greenville Memorial Hospital

🇺🇸

Greenville, South Carolina, United States

Prisma Health Cancer Institute - Eastside

🇺🇸

Greenville, South Carolina, United States

Prisma Health Cancer Institute - Greer

🇺🇸

Greer, South Carolina, United States

Gibbs Cancer Center-Pelham

🇺🇸

Greer, South Carolina, United States

Rock Hill Radiation Therapy Center

🇺🇸

Rock Hill, South Carolina, United States

Levine Cancer Institute-Rock Hill

🇺🇸

Rock Hill, South Carolina, United States

Prisma Health Cancer Institute - Seneca

🇺🇸

Seneca, South Carolina, United States

Spartanburg Medical Center

🇺🇸

Spartanburg, South Carolina, United States

SMC Center for Hematology Oncology Union

🇺🇸

Union, South Carolina, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

Memorial Hospital

🇺🇸

Chattanooga, Tennessee, United States

Baptist Memorial Hospital and Cancer Center-Collierville

🇺🇸

Collierville, Tennessee, United States

Vanderbilt-Ingram Cancer Center Cool Springs

🇺🇸

Franklin, Tennessee, United States

Pulmonary Medicine Center of Chattanooga-Hixson

🇺🇸

Hixson, Tennessee, United States

Baptist Memorial Hospital and Cancer Center-Memphis

🇺🇸

Memphis, Tennessee, United States

Vanderbilt Breast Center at One Hundred Oaks

🇺🇸

Nashville, Tennessee, United States

Vanderbilt University/Ingram Cancer Center

🇺🇸

Nashville, Tennessee, United States

Memorial GYN Plus

🇺🇸

Ooltewah, Tennessee, United States

Saint Joseph Regional Cancer Center

🇺🇸

Bryan, Texas, United States

Parkland Memorial Hospital

🇺🇸

Dallas, Texas, United States

UT Southwestern/Simmons Cancer Center-Dallas

🇺🇸

Dallas, Texas, United States

UT Southwestern/Simmons Cancer Center-Fort Worth

🇺🇸

Fort Worth, Texas, United States

M D Anderson Cancer Center

🇺🇸

Houston, Texas, United States

UT Southwestern Clinical Center at Richardson/Plano

🇺🇸

Richardson, Texas, United States

American Fork Hospital / Huntsman Intermountain Cancer Center

🇺🇸

American Fork, Utah, United States

Sandra L Maxwell Cancer Center

🇺🇸

Cedar City, Utah, United States

Farmington Health Center

🇺🇸

Farmington, Utah, United States

Logan Regional Hospital

🇺🇸

Logan, Utah, United States

Intermountain Medical Center

🇺🇸

Murray, Utah, United States

McKay-Dee Hospital Center

🇺🇸

Ogden, Utah, United States

Utah Valley Regional Medical Center

🇺🇸

Provo, Utah, United States

Riverton Hospital

🇺🇸

Riverton, Utah, United States

Saint George Regional Medical Center

🇺🇸

Saint George, Utah, United States

University of Utah Sugarhouse Health Center

🇺🇸

Salt Lake City, Utah, United States

Utah Cancer Specialists-Salt Lake City

🇺🇸

Salt Lake City, Utah, United States

Huntsman Cancer Institute/University of Utah

🇺🇸

Salt Lake City, Utah, United States

LDS Hospital

🇺🇸

Salt Lake City, Utah, United States

Central Vermont Medical Center/National Life Cancer Treatment

🇺🇸

Berlin, Vermont, United States

Pacific Gynecology Specialists

🇺🇸

Seattle, Washington, United States

University of Vermont Medical Center

🇺🇸

Burlington, Vermont, United States

University of Vermont and State Agricultural College

🇺🇸

Burlington, Vermont, United States

Dartmouth Cancer Center - North

🇺🇸

Saint Johnsbury, Vermont, United States

Sovah Health Martinsville

🇺🇸

Martinsville, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center

🇺🇸

Richmond, Virginia, United States

VCU Community Memorial Health Center

🇺🇸

South Hill, Virginia, United States

Providence Regional Cancer System-Aberdeen

🇺🇸

Aberdeen, Washington, United States

MultiCare Auburn Medical Center

🇺🇸

Auburn, Washington, United States

Overlake Medical Center

🇺🇸

Bellevue, Washington, United States

PeaceHealth Saint Joseph Medical Center

🇺🇸

Bellingham, Washington, United States

Highline Medical Center-Main Campus

🇺🇸

Burien, Washington, United States

Providence Regional Cancer System-Centralia

🇺🇸

Centralia, Washington, United States

Swedish Cancer Institute-Edmonds

🇺🇸

Edmonds, Washington, United States

Saint Elizabeth Hospital

🇺🇸

Enumclaw, Washington, United States

Providence Regional Cancer Partnership

🇺🇸

Everett, Washington, United States

Saint Francis Hospital

🇺🇸

Federal Way, Washington, United States

MultiCare Gig Harbor Medical Park

🇺🇸

Gig Harbor, Washington, United States

Swedish Cancer Institute-Issaquah

🇺🇸

Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology

🇺🇸

Kennewick, Washington, United States

Providence Regional Cancer System-Lacey

🇺🇸

Lacey, Washington, United States

Saint Clare Hospital

🇺🇸

Lakewood, Washington, United States

PeaceHealth Saint John Medical Center

🇺🇸

Longview, Washington, United States

Jefferson Healthcare

🇺🇸

Port Townsend, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

🇺🇸

Poulsbo, Washington, United States

MultiCare Good Samaritan Hospital

🇺🇸

Puyallup, Washington, United States

Valley Medical Center

🇺🇸

Renton, Washington, United States

Swedish Medical Center-Ballard Campus

🇺🇸

Seattle, Washington, United States

Fred Hutchinson Cancer Center

🇺🇸

Seattle, Washington, United States

Kaiser Permanente Washington

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Cherry Hill

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-First Hill

🇺🇸

Seattle, Washington, United States

University of Washington Medical Center - Montlake

🇺🇸

Seattle, Washington, United States

PeaceHealth United General Medical Center

🇺🇸

Sedro-Woolley, Washington, United States

Providence Regional Cancer System-Shelton

🇺🇸

Shelton, Washington, United States

Saint Michael Cancer Center

🇺🇸

Silverdale, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Valley

🇺🇸

Spokane Valley, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Downtown

🇺🇸

Spokane, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - North

🇺🇸

Spokane, Washington, United States

Franciscan Research Center-Northwest Medical Plaza

🇺🇸

Tacoma, Washington, United States

Mary Bridge Children's Hospital and Health Center

🇺🇸

Tacoma, Washington, United States

MultiCare Tacoma General Hospital

🇺🇸

Tacoma, Washington, United States

Northwest Medical Specialties PLLC

🇺🇸

Tacoma, Washington, United States

PeaceHealth Southwest Medical Center

🇺🇸

Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center

🇺🇸

Walla Walla, Washington, United States

Providence Regional Cancer System-Yelm

🇺🇸

Yelm, Washington, United States

United Hospital Center

🇺🇸

Bridgeport, West Virginia, United States

West Virginia University Charleston Division

🇺🇸

Charleston, West Virginia, United States

WVUH-Berkely Medical Center

🇺🇸

Martinsburg, West Virginia, United States

West Virginia University Healthcare

🇺🇸

Morgantown, West Virginia, United States

Camden Clark Medical Center

🇺🇸

Parkersburg, West Virginia, United States

ThedaCare Regional Cancer Center

🇺🇸

Appleton, Wisconsin, United States

Duluth Clinic Ashland

🇺🇸

Ashland, Wisconsin, United States

Northwest Wisconsin Cancer Center

🇺🇸

Ashland, Wisconsin, United States

Aurora Cancer Care-Southern Lakes VLCC

🇺🇸

Burlington, Wisconsin, United States

HSHS Sacred Heart Hospital

🇺🇸

Eau Claire, Wisconsin, United States

Marshfield Medical Center-EC Cancer Center

🇺🇸

Eau Claire, Wisconsin, United States

Aurora Health Center-Fond du Lac

🇺🇸

Fond Du Lac, Wisconsin, United States

Aurora Health Care Germantown Health Center

🇺🇸

Germantown, Wisconsin, United States

Aurora Cancer Care-Grafton

🇺🇸

Grafton, Wisconsin, United States

Bellin Memorial Hospital

🇺🇸

Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay

🇺🇸

Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's

🇺🇸

Green Bay, Wisconsin, United States

Aurora BayCare Medical Center

🇺🇸

Green Bay, Wisconsin, United States

University of Wisconsin Carbone Cancer Center - Johnson Creek

🇺🇸

Johnson Creek, Wisconsin, United States

Aurora Cancer Care-Kenosha South

🇺🇸

Kenosha, Wisconsin, United States

Gundersen Lutheran Medical Center

🇺🇸

La Crosse, Wisconsin, United States

University of Wisconsin Carbone Cancer Center - University Hospital

🇺🇸

Madison, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette

🇺🇸

Marinette, Wisconsin, United States

Marshfield Medical Center-Marshfield

🇺🇸

Marshfield, Wisconsin, United States

Aurora Cancer Care-Milwaukee

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Saint Luke's Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Marshfield Medical Center - Minocqua

🇺🇸

Minocqua, Wisconsin, United States

ProHealth D N Greenwald Center

🇺🇸

Mukwonago, Wisconsin, United States

Cancer Center of Western Wisconsin

🇺🇸

New Richmond, Wisconsin, United States

ProHealth Oconomowoc Memorial Hospital

🇺🇸

Oconomowoc, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh

🇺🇸

Oshkosh, Wisconsin, United States

Aurora Cancer Care-Racine

🇺🇸

Racine, Wisconsin, United States

Marshfield Medical Center-Rice Lake

🇺🇸

Rice Lake, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan

🇺🇸

Sheboygan, Wisconsin, United States

Marshfield Medical Center-River Region at Stevens Point

🇺🇸

Stevens Point, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Sturgeon Bay

🇺🇸

Sturgeon Bay, Wisconsin, United States

Aurora Medical Center in Summit

🇺🇸

Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers

🇺🇸

Two Rivers, Wisconsin, United States

ProHealth Waukesha Memorial Hospital

🇺🇸

Waukesha, Wisconsin, United States

UW Cancer Center at ProHealth Care

🇺🇸

Waukesha, Wisconsin, United States

Marshfield Clinic-Wausau Center

🇺🇸

Wausau, Wisconsin, United States

Aurora Cancer Care-Milwaukee West

🇺🇸

Wauwatosa, Wisconsin, United States

Aurora West Allis Medical Center

🇺🇸

West Allis, Wisconsin, United States

Marshfield Medical Center - Weston

🇺🇸

Weston, Wisconsin, United States

Cheyenne Regional Medical Center-West

🇺🇸

Cheyenne, Wyoming, United States

Billings Clinic-Cody

🇺🇸

Cody, Wyoming, United States

Welch Cancer Center

🇺🇸

Sheridan, Wyoming, United States

Arthur J E Child Comprehensive Cancer Centre

🇨🇦

Calgary, Alberta, Canada

BCCA-Vancouver Cancer Centre

🇨🇦

Vancouver, British Columbia, Canada

Doctor H. Bliss Murphy Cancer Centre

🇨🇦

St. John's, Newfoundland and Labrador, Canada

London Regional Cancer Program

🇨🇦

London, Ontario, Canada

Ottawa Hospital and Cancer Center-General Campus

🇨🇦

Ottawa, Ontario, Canada

Algoma District Cancer Program Sault Area Hospital

🇨🇦

Sault Ste Marie, Ontario, Canada

University Health Network-Princess Margaret Hospital

🇨🇦

Toronto, Ontario, Canada

Allan Blair Cancer Centre

🇨🇦

Regina, Saskatchewan, Canada

Saskatoon Cancer Centre

🇨🇦

Saskatoon, Saskatchewan, Canada

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