Observational Study to Detect Postoperative Residual Curarization in Infantile Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Residual paralysis
研究概览
简要总结
The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.
详细描述
Residual neuromuscular block is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents. Aim of this prospective, observational study is to detect the incidence and severity of residual paralysis at a tertiary academic german university medical center.
Methods:
All infantile patients recieving neuromuscular blocking agents are included over a 12 week observational period. At the end of the operation procedure, directly prior to tracheal extubation a train-of-four ratio was assessed quantitatively by an independet observer using the TOF Watch SX monitor. Data related to patient postoperative outcome were collected in the operating theatre, during the way to the postoperative care unit (PACU) and during the stay in the PACU:
- incidence of residual paralysis
- incidence of aspiration, bronchospasm, laryngospasm, oxygen desaturation, airway obstruction,
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •General aneasthesia with muscle relaxation
- •Children between 1 Month to 18 Years
- •Endotracheal Intubation due to surgical or diagnostical procedures
排除标准
- •older than 18 years
- •local aneasthesia
- •regional aneasthesia
- •larynx mask
- •patient comes from ICU
- •children who are not planned to be extubated
结局指标
主要结局
Residual paralysis
时间窗: Directly prior to extubation
Rate of residual paralysis after extubation of the infantile patients measured by acceleromyography.
次要结局
- Airway obstruction(1, 10, 30, 60 minutes after extubation)
- Oxygen desaturation(1, 10, 30, 60 minutes after extubation)
- Bronchospasm, laryngospasm(1, 10, 30, 60 minutes after extubation)
研究者
Christoph Unterbuchner
Principal Investigator, Dr. med. Christoph Unterbuchner, Staff Anaesthesiologist
University of Regensburg