Observational Study to Detect Postoperative Residual Curarization in Infantile Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Residual Curarization
- Sponsor
- University of Regensburg
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Residual paralysis
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.
Detailed Description
Residual neuromuscular block is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents. Aim of this prospective, observational study is to detect the incidence and severity of residual paralysis at a tertiary academic german university medical center. Methods: All infantile patients recieving neuromuscular blocking agents are included over a 12 week observational period. At the end of the operation procedure, directly prior to tracheal extubation a train-of-four ratio was assessed quantitatively by an independet observer using the TOF Watch SX monitor. Data related to patient postoperative outcome were collected in the operating theatre, during the way to the postoperative care unit (PACU) and during the stay in the PACU: * incidence of residual paralysis * incidence of aspiration, bronchospasm, laryngospasm, oxygen desaturation, airway obstruction,
Investigators
Christoph Unterbuchner
Principal Investigator, Dr. med. Christoph Unterbuchner, Staff Anaesthesiologist
University of Regensburg
Eligibility Criteria
Inclusion Criteria
- •General aneasthesia with muscle relaxation
- •Children between 1 Month to 18 Years
- •Endotracheal Intubation due to surgical or diagnostical procedures
Exclusion Criteria
- •older than 18 years
- •local aneasthesia
- •regional aneasthesia
- •larynx mask
- •patient comes from ICU
- •children who are not planned to be extubated
Outcomes
Primary Outcomes
Residual paralysis
Time Frame: Directly prior to extubation
Rate of residual paralysis after extubation of the infantile patients measured by acceleromyography.
Secondary Outcomes
- Airway obstruction(1, 10, 30, 60 minutes after extubation)
- Oxygen desaturation(1, 10, 30, 60 minutes after extubation)
- Bronchospasm, laryngospasm(1, 10, 30, 60 minutes after extubation)