NCT03595306已完成不适用
Human Gut Microbiota and Prebiotic Response
Duke University2 个研究点 分布在 1 个国家目标入组 41 人开始时间: 2018年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- change in levels of SCFAs in stool samples
研究概览
简要总结
This study is designed to examine the shift in gut microbiota and their metabolism after consumption of a dietary supplement (prebiotic) by healthy participants. The investigators will provide participants with a panel of over the counter prebiotics and monitor their gut microbiome response in stool. All prebiotics will be commercially available, over-the-counter food, food additives, or dietary supplements, without any known market-use adverse effects beyond minimal discomfort.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 17 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Provide Stool Samples at no risk to yourself
排除标准
- •No oral antibiotic treatments within previous 1 month
- •No known allergy to milk products or lactose intolerance
- •no known allergy to wheat or gluten intolerance
- •no history of irritable bowel syndrome
- •no history of inflammatory bowel disease
- •no history of type-2 diabetes
- •no history of chronic kidney disease or reduced kidney function
- •no current intestinal obstructions
- •no current untreated colorectal cancer
- •not currently pregnant or breastfeeding
结局指标
主要结局
change in levels of SCFAs in stool samples
时间窗: Baseline and 6 weeks
次要结局
- change in levels of cytokines in stool samples(Baseline and 6 weeks)
研究者
研究点 (2)
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