Effects of Different Inspiratory Muscle Training Protocols on Functional Exercise Capacity and Respiratory and Peripheral Muscle Strength in Patients With Chronic Kidney Disease: A Randomized Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Kidney Diseases
- Sponsor
- Mustafa Kemal University
- Enrollment
- 47
- Locations
- 1
- Primary Endpoint
- Inspiratory muscle strength
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The goal of this study is to investigate the effects of different IMT protocols on respiratory muscle strength, functional exercise capacity, quadriceps femoris muscle strength (QMS), handgrip muscle strength (HGS), QoL, respiratory function, dyspnoea, fatigue, balance, and PA levels in patients with CKD that were not on dialysis.
Detailed Description
Peripheral and respiratory muscle weakness has been reported in patients with chronic kidney disease (CKD). Management of respiratory muscle weakness is crucial, as reduced functional performance is related to respiratory muscle weakness. Different IMT function protocols with 30-70% of the maximal inspiratory pressure (MIP) have been found to improve these in patients with CKD. The most efficient IMT intensity for patients with CKD is unknown. Therefore, this study aims to investigate the effects of different IMT protocols on respiratory muscle strength, functional exercise capacity, quadriceps femoris muscle strength (QMS), handgrip muscle strength (HGS), QoL, respiratory function, dyspnoea, fatigue, balance, and PA levels in patients with CKD that were not on dialysis.
Investigators
Nihan Katayıfçı
assistant professor
Mustafa Kemal University
Eligibility Criteria
Inclusion Criteria
- •Patients with CKD stages 1-5 based on the CKD staging proposed by the Kidney Disease Outcomes Quality Initiative who are not on dialysis
- •Aged\>18 years
- •No change in medications over one month
Exclusion Criteria
- •Uncontrolled hypertension
- •Non-stable cardiac disease
- •Recent viral infections
- •Respiratory, neurological, and orthopedic diseases
- •Pregnant and lactating patients
Outcomes
Primary Outcomes
Inspiratory muscle strength
Time Frame: First day
A mouth pressure device will be used to evaluate IMS.
Secondary Outcomes
- Pulmonary functions FVC(First day)
- Expiratory muscle strength(First day)
- Dyspnoea(First day)
- Fatigue(First day)
- Peripheral muscle strength(First day)
- Pulmonary functions FEF25-75%(First day)
- Pulmonary functions FEV1(First day)
- Pulmonary functions FEV1/FVC(First day)
- Functional exercise capacity(First day)
- Pulmonary functions PEF(First day)
- Quality of life assessment(First day)
- Physical activity(First day)
- Balance(First day)