Effects of Different Inspiratory Muscle Training Protocols on Functional Exercise Capacity and Respiratory and Peripheral Muscle Strength in Patients With Chronic Kidney Disease: A Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 2
- 主要终点
- Inspiratory muscle strength
研究概览
简要总结
The goal of this study is to investigate the effects of different IMT protocols on respiratory muscle strength, functional exercise capacity, quadriceps femoris muscle strength (QMS), handgrip muscle strength (HGS), QoL, respiratory function, dyspnoea, fatigue, balance, and PA levels in patients with CKD that were not on dialysis.
详细描述
Peripheral and respiratory muscle weakness has been reported in patients with chronic kidney disease (CKD). Management of respiratory muscle weakness is crucial, as reduced functional performance is related to respiratory muscle weakness.
Different IMT function protocols with 30-70% of the maximal inspiratory pressure (MIP) have been found to improve these in patients with CKD. The most efficient IMT intensity for patients with CKD is unknown. Therefore, this study aims to investigate the effects of different IMT protocols on respiratory muscle strength, functional exercise capacity, quadriceps femoris muscle strength (QMS), handgrip muscle strength (HGS), QoL, respiratory function, dyspnoea, fatigue, balance, and PA levels in patients with CKD that were not on dialysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
The patients will be not informed about their groups and they will be evaluated and trained at different places and times
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with CKD stages 1-5 based on the CKD staging proposed by the Kidney Disease Outcomes Quality Initiative who are not on dialysis
- •Aged>18 years
- •No change in medications over one month
排除标准
- •Uncontrolled hypertension
- •Non-stable cardiac disease
- •Recent viral infections
- •Respiratory, neurological, and orthopedic diseases
- •Pregnant and lactating patients
结局指标
主要结局
Inspiratory muscle strength
时间窗: First day
A mouth pressure device will be used to evaluate IMS.
次要结局
- Pulmonary functions FVC(First day)
- Expiratory muscle strength(First day)
- Dyspnoea(First day)
- Fatigue(First day)
- Peripheral muscle strength(First day)
- Pulmonary functions FEF25-75%(First day)
- Pulmonary functions FEV1(First day)
- Pulmonary functions FEV1/FVC(First day)
- Functional exercise capacity(First day)
- Pulmonary functions PEF(First day)
- Quality of life assessment(First day)
- Physical activity(First day)
- Balance(First day)
研究者
Nihan Katayıfçı
assistant professor
Mustafa Kemal University