Effect of Scalp Nerve Block Combined With Intercostal Nerve Block on Quality of Recovery After Deep Brain Stimulation in Patients With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- The 15-item QoR score
研究概览
简要总结
Patients diagnosed with Parkinson's disease (PD) undergoing deep Brain Stimulation (DBS) have a higher risk of perioperative complications and postoperative pain will affect quality of recovery (QoR) resulting in longer hospitalization time and higher hospital costs. Scalp nerve block (SNB) combined with intercostal nerve block (ICNB)can alleviate postoperative pain while effect of them on postoperative recovery quality of patients diagnosed with PD was unclear. Therefore, the investigators conducted a randomized controlled trails to provide a novel method for enhanced recovery and early prevention and treatment of acute pain after DBS surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with PD who receive elective deep brain stimulation (DBS) surgery
- •Aged ≥ 18
- •American Society of Anesthesiologists (ASA) physical status of I-III
- •Able to communicate normally
排除标准
- •Allergy to local anesthetics
- •Pre-existing infection at block site
- •Severe coagulopathy
- •Pre-existing neuropathic pain condition
- •Previous history of DBS surgery
- •unwilling to provide informed consent or poor compliance
结局指标
主要结局
The 15-item QoR score
时间窗: 24 hour after surgery
The 15-item QoR score is used to asses quality of recovery after surgery which ranges 0-150 and higher QoR-15 scores indicate better postoperative recovery
次要结局
- The patients with PONV(24 hour after surgery)
- Consumption of opioid(during operation)
- The 15-item QoR score(72 hour and 1 month after surgery)
- The NRS score(before discharge from PACU, at 24 hour, 72 hour and 1 month after surgery)
研究者
Wen-bin Lu, MD
Attending doctor
Changhai Hospital